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ATG4A Produits

(Autophagy related 4A Cysteine Peptidase (ATG4A))

Catégories

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified. [provided by RefSeq, Jul 2008].

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Catégories ATG4A en vedette

ATG4A Anticorps

High quality antibodies with extensive validation data.

ATG4A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ATG4A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, ICC, FACS
Validations
  • (5)
N° du produit ABIN7193210
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
N° du produit ABIN388493
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
N° du produit ABIN7193211
Quantité 100 μL
Fiche technique Fiche technique

ATG4A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951537
Quantité 96 tests
Fiche technique Fiche technique

ATG4A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121951
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1345970
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7318185
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits ATG4A

Guo, Zhou, Gao, Zhang, Wei, Hong, Chu, Duan, Zhang, Xu: "MicroRNA-144-3p inhibits autophagy activation and enhances Bacillus Calmette-Guérin infection by targeting ATG4a in RAW264.7 macrophage cells." dans: PLoS ONE, Vol. 12, Issue 6, pp. e0179772, (2017) (PubMed).

Bortnik, Choutka, Horlings, Leung, Baker, Lebovitz, Dragowska, Go, Bally, Minchinton, Gelmon, Gorski: "Identification of breast cancer cell subtypes sensitive to ATG4B inhibition." dans: Oncotarget, Vol. 7, Issue 41, pp. 66970-66988, (2016) (PubMed).

Li, Hou, Wang, Chen, Shao, Yin: "Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates." dans: The Journal of biological chemistry, Vol. 286, Issue 9, pp. 7327-38, (2011) (PubMed).

Lum, DeBerardinis, Thompson: "Autophagy in metazoans: cell survival in the land of plenty." dans: Nature reviews. Molecular cell biology, Vol. 6, Issue 6, pp. 439-48, (2005) (PubMed).

Baehrecke: "Autophagy: dual roles in life and death?" dans: Nature reviews. Molecular cell biology, Vol. 6, Issue 6, pp. 505-10, (2005) (PubMed).

Greenberg: "Degrade or die: a dual function for autophagy in the plant immune response." dans: Developmental cell, Vol. 8, Issue 6, pp. 799-801, (2005) (PubMed).

Shintani, Klionsky: "Autophagy in health and disease: a double-edged sword." dans: Science (New York, N.Y.), Vol. 306, Issue 5698, pp. 990-5, (2004) (PubMed).

Scherz-Shouval, Sagiv, Shorer, Elazar: "The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A." dans: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 14053-8, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à ATG4A

autophagy related 4A cysteine peptidase L homeolog (atg4a.L), autophagy related 4A cysteine peptidase (ATG4A), Peptidase family C54 protein (AT2G44140), ATG4 autophagy related 4 homolog A (S. cerevisiae) (atg4a), autophagy related 4A, cysteine peptidase (atg4a), autophagy related 4A, cysteine peptidase (Atg4a), AI627006, apg4a, APG4A, Apg4a, Atg4a, Atg4al, Aut2a, autl2, AUTL2, Autl2, AV169859, F6E13.27, zgc:111958

Protein level used designations for ATG4A

  • ATG4 autophagy related 4 homolog A
  • autophagy-related protein 4 homolog A
  • cysteine protease ATG4A
  • autophagy-related cysteine endopeptidase 2
  • Cysteine protease ATG4A
  • autophagin-2A
  • autophagy-related cysteine endopeptidase 2A
  • bAut2A
  • APG4 autophagy 4 homolog A
  • AUT-like 2 cysteine endopeptidase
  • AUT-like 2, cysteine endopeptidase
  • autophagin 2
  • autophagin-2
  • hAPG4A
  • APG4 (ATG4) autophagy-related homolog A
  • autophagy 4 homolog A
  • autophagy-related 4A
  • cysteine protease APG4A
  • autophagy related 4 homolog A
  • autophagy related 4A, cysteine peptidase
  • uncharacterized protein LOC678769
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