ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Produits
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B))
Catégories
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B en vedette
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Anticorps
High quality antibodies with extensive validation data.
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (4)
- (4)
N° du produit
ABIN670161
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (1)
N° du produit
ABIN686977
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Plasmodium falciparum
Application
ELISA
Validations
N° du produit
ABIN7178310
Quantité
100 μg
Fiche technique
Fiche technique
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3132560
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN5712796
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Entamoeba histolytica
Source
Yeast
Validations
- (1)
N° du produit
ABIN5713190
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B
: "The impact of insulin on chemotherapeutic sensitivity to 5-fluorouracil in gastric cancer cell lines SGC7901, MKN45 and MKN28." dans: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 64, (2016) (PubMed).: "MicroRNA-186 induces sensitivity of ovarian cancer cells to paclitaxel and cisplatin by targeting ABCB1." dans: Journal of ovarian research, Vol. 8, pp. 80, (2016) (PubMed).
: "Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice." dans: Scientific reports, Vol. 5, pp. 13558, (2016) (PubMed).
: "Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0131579, (2015) (PubMed).
: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." dans: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).
: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B
ATP binding cassette subfamily B member 1 (ABCB1), ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b), ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b), ABC20, Abcb1, CD243, CLCS, GP170, mdr, MDR1, Mdr1, Mdr1b, P-GP, Pgy-1, PGY1, Pgy1Protein level used designations for ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B
- P-glycoprotein 1
- colchicin sensitivity
- doxorubicin resistance
- multidrug resistance protein 1
- ATP-binding cassette sub-family B member 1
- P glycoprotein 1
- multidrug resistance protein 1B
- ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1)
- ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1)
- ATP-binding cassette, sub-family B (MDR/TAP), member 1B
- ATP-binding cassette, subfamily B, member 1B
- P-glycoprotein/multidrug resistance 1
Avez-vous cherché autre chose?
Vous êtes ici:
