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ATP2A1/SERCA1 Produits

(ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Catégories ATP2A1/SERCA1 en vedette

ATP2A1/SERCA1 Anticorps

High quality antibodies with extensive validation data.

ATP2A1/SERCA1 Kits ELISA

Reliable ELISA kits for a wide range of species.

ATP2A1/SERCA1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ATP2A1/SERCA1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (6)
N° du produit ABIN559993
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
  • (3)
N° du produit ABIN1881089
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (4)
N° du produit ABIN5611123
Quantité 100 μL
Fiche technique Fiche technique

ATP2A1/SERCA1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965083
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method
Validations
N° du produit ABIN1156500
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1156502
Quantité 96 tests
Fiche technique Fiche technique

ATP2A1/SERCA1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346035
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346033
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3109714
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ATP2A1/SERCA1

Salanova, Schiffl, Blottner: "Atypical fast SERCA1a protein expression in slow myofibers and differential S-nitrosylation prevented by exercise during long term bed rest." dans: Histochemistry and cell biology, Vol. 132, Issue 4, pp. 383-94, (2009) (PubMed).

Chami, Oulès, Szabadkai, Tacine, Rizzuto, Paterlini-Bréchot: "Role of SERCA1 truncated isoform in the proapoptotic calcium transfer from ER to mitochondria during ER stress." dans: Molecular cell, Vol. 32, Issue 5, pp. 641-51, (2008) (PubMed).

Thorleifsson, Walters, Gudbjartsson, Steinthorsdottir, Sulem, Helgadottir, Styrkarsdottir, Gretarsdottir, Thorlacius, Jonsdottir, Jonsdottir, Olafsdottir, Olafsdottir, Jonsson, Jonsson et al.: "Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity...." dans: Nature genetics, Vol. 41, Issue 1, pp. 18-24, (2008) (PubMed).

Brandl, Green, Korczak, MacLennan: "Two Ca2+ ATPase genes: homologies and mechanistic implications of deduced amino acid sequences." dans: Cell, Vol. 44, Issue 4, pp. 597-607, (1986) (PubMed).

Synonymes et noms alternatifs relatifs à ATP2A1/SERCA1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (atp2a1), ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 (ATP2A1), ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 S homeolog (atp2a2.S), ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 (Atp2a1), atp2a, ATP2A, ATP2A1, atp2a2, ATP2A3, atp2b, ca-p60a, cb279, dar, serca, serca1, SERCA1, Serca1, SERCA1a, serca2, wu:cegs655, wu:fb17h11, wu:fb19b10, zgc:92110

Protein level used designations for ATP2A1/SERCA1

  • ATPase, Ca++ transporting, fast twitch 1
  • acc
  • accordion
  • sarcoendoplasmic reticulum calcium ATPase
  • ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
  • ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
  • sarcoplasmic/endoplasmic reticulum calcium ATPase 1-like
  • ATPase, Ca++ transporting, slow twitch 2
  • sarcoplasmic/endoplasmic reticulum calcium ATPase 1
  • ATPase, Ca++ transporting, ubiquitous
  • SERCA1
  • SR Ca(2+)-ATPase 1
  • calcium pump 1
  • calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform
  • endoplasmic reticulum class 1/2 Ca(2+) ATPase
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