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ATP2B2 Produits

(ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Catégories ATP2B2 en vedette

ATP2B2 Anticorps

High quality antibodies with extensive validation data.

ATP2B2 Kits ELISA

Reliable ELISA kits for a wide range of species.

ATP2B2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ATP2B2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7436264
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN1385852
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (2)
N° du produit ABIN7163515
Quantité 100 μL
Fiche technique Fiche technique

ATP2B2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953996
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5674663
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN2850984
Quantité 96 tests
Fiche technique Fiche technique

ATP2B2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7408519
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7398914
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3114272
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ATP2B2

Schmidt, Kollewe, Constantin, Henrich, Ritzau-Jost, Bildl, Saalbach, Hallermann, Kulik, Fakler, Schulte: "Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance." dans: Neuron, Vol. 96, Issue 4, pp. 827-838.e9, (2017) (PubMed).

Pérez-Cañamás, Benvegnù, Rueda, Rábano, Satrústegui, Ledesma: "Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease." dans: Molecular psychiatry, (2016) (PubMed).

Guo, Du, Wu, Jiang, Bi: "Disrupted calcium homeostasis is involved in elevated zinc ion-induced photoreceptor cell death." dans: Archives of biochemistry and biophysics, Vol. 560, pp. 44-51, (2014) (PubMed).

Guo, Bi, Wang, Wu: "Zinc oxide nanoparticles decrease the expression and activity of plasma membrane calcium ATPase, disrupt the intracellular calcium homeostasis in rat retinal ganglion cells." dans: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1849-59, (2013) (PubMed).

Filoteo, Elwess, Enyedi, Caride, Aung, Penniston: "Plasma membrane Ca2+ pump in rat brain. Patterns of alternative splices seen by isoform-specific antibodies." dans: The Journal of biological chemistry, Vol. 272, Issue 38, pp. 23741-7, (1997) (PubMed).

Hilfiker, Guerini, Carafoli: "Cloning and expression of isoform 2 of the human plasma membrane Ca2+ ATPase. Functional properties of the enzyme and its splicing products." dans: The Journal of biological chemistry, Vol. 269, Issue 42, pp. 26178-83, (1994) (PubMed).

Stauffer, Hilfiker, Carafoli, Strehler: "Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes." dans: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25993-6003, (1994) (PubMed).

Shull, Greeb: "Molecular cloning of two isoforms of the plasma membrane Ca2+-transporting ATPase from rat brain. Structural and functional domains exhibit similarity to Na+,K+- and other cation transport ATPases." dans: The Journal of biological chemistry, Vol. 263, Issue 18, pp. 8646-57, (1988) (PubMed).

Synonymes et noms alternatifs relatifs à ATP2B2

ATPase plasma membrane Ca2+ transporting 2 (ATP2B2), ATPase, Ca++ transporting, plasma membrane 2 (Atp2b2), ATPase plasma membrane Ca2+ transporting 2 (Atp2b2), ATPase, Ca++ transporting, plasma membrane 2 (atp2b2), ATPase plasma membrane Ca2+ transporting 2 (atp2b2), ATP2B2, ATP2B4, D6Abb2e, dfw, jog, PMCA, PMCA2, PMCA2a, PMCA2i, Tmy, wms, wri

Protein level used designations for ATP2B2

  • plasma membrane Ca(2+)-ATPase
  • plasma membrane Ca2+ pump 2
  • plasma membrane calcium ATPase
  • plasma membrane calcium pump
  • plasma membrane calcium-transporting ATPase 2
  • ATPase, Ca++ transporting, plasma membrane 4
  • plasma membrane calcium ATPase 2
  • ATPase, Ca++ transporting, plasma membrane 2
  • plasma membrane calcium-transporting ATPase 4
  • deaf waddler
  • wriggle
  • ATPase isoform 2 Na+K+ transporting beta polypeptide 2
  • ATPase isoform 2, Na+K+ transporting, beta polypeptide 2
  • plasma membrane Ca++-ATPase
  • pmca2
  • plasma membrane calcium-transporting ATPase 2-like
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