ATPase, H+ Transporting, Lysosomal V0 Subunit A1 Produits
(ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1))
Catégories
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories ATPase, H+ Transporting, Lysosomal V0 Subunit A1 en vedette
ATPase, H+ Transporting, Lysosomal V0 Subunit A1 Anticorps
High quality antibodies with extensive validation data.
ATPase, H+ Transporting, Lysosomal V0 Subunit A1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ATPase, H+ Transporting, Lysosomal V0 Subunit A1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Cow, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (4)
N° du produit
ABIN2780008
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
- (1)
N° du produit
ABIN560006
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Human, Mouse, Pig, Rat
Application
WB
Validations
- (1)
N° du produit
ABIN6744589
Quantité
100 μL
Fiche technique
Fiche technique
ATPase, H+ Transporting, Lysosomal V0 Subunit A1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1346095
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3117162
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2715049
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ATPase, H+ Transporting, Lysosomal V0 Subunit A1
: "Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification." dans: Nature cell biology, Vol. 21, Issue 3, pp. 384-396, (2019) (PubMed).: "Isoform-specific gene disruptions reveal a role for the V-ATPase subunit a4 isoform in the invasiveness of 4T1-12B breast cancer cells." dans: The Journal of biological chemistry, Vol. 294, Issue 29, pp. 11248-11258, (2019) (PubMed).
: "ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons." dans: Cell death & disease, Vol. 9, Issue 6, pp. 626, (2019) (PubMed).
: "Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model." dans: Nature communications, Vol. 8, pp. 14612, (2017) (PubMed).
: "An animal homolog of plant Mep/Amt transporters promotes ammonia excretion by the anal papillae of the disease vector mosquito Aedes aegypti." dans: The Journal of experimental biology, Vol. 219, Issue Pt 9, pp. 1346-55, (2016) (PubMed).
: "POLR2F, ATP6V0A1 and PRNP expression in colorectal cancer: new molecules with prognostic significance?" dans: Anticancer research, Vol. 28, Issue 2B, pp. 1221-7, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à ATPase, H+ Transporting, Lysosomal V0 Subunit A1
ATPase H+ transporting V0 subunit a1 (ATP6V0A1), ATPase, H+ transporting, lysosomal V0 subunit A1 (Atp6v0a1), ATPase H+ transporting V0 subunit a1 (Atp6v0a1), si:ch73-173p19.2 (si:ch73-173p19.2), ATPase, H+ transporting, lysosomal V0 subunit a1 L homeolog (atp6v0a1.L), ATPase, H+ transporting, lysosomal V0 subunit a1b (atp6v0a1b), ATPase, H+ transporting, lysosomal V0 subunit a1a (atp6v0a1a), a1, A1, AA959968, ATP6a1, ATP6N1, Atp6n1, ATP6N1A, Atp6n1a, atp6v0a1, Atpv0a1, Stv1, Vph1, Vpp-1, VPP1, Vpp1, wu:fc25b09, wu:fj37e01, zgc:76965, zgc:112214Protein level used designations for ATPase, H+ Transporting, Lysosomal V0 Subunit A1
- ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1A (110/116kD)
- ATPase, H+ transporting, lysosomal non-catalytic accessory protein 1 (110/116kD)
- H(+)-transporting two-sector ATPase, 116 kDa accessory protein A1
- V-ATPase 116 kDa
- V-type proton ATPase 116 kDa subunit a
- V-type proton ATPase 116 kDa subunit a isoform 1
- clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit
- vacuolar adenosine triphosphatase subunit Ac116
- vacuolar proton pump subunit 1
- vacuolar proton pump, subunit 1
- vacuolar proton translocating ATPase 116 kDa subunit A
- vacuolar-type H(+)-ATPase 115 kDa subunit
- ATPase, H+ transporting, lysosomal (vacuolar proton pump) noncatalytic accessory protein 1 (110/160 kDa)
- ATPase, H+ transporting, lysosomal (vacuolar proton pump) noncatalytic accessory protein 1A (110/160 kDa)
- ATPase, H+ transporting, lysosomal V0 subunit a
- V-ATPase a1
- vacuolar proton translocating ATPase 116 kDa subunit a
- ATPase H+ transporting lysosomal (vacuolar proton pump) noncatalytic accessory protein 1 (110/160 kDa)
- ATPase, H+ transporting, lysosomal noncatalytic accessory protein 1a
- v-H+ATPase subunit a1
- vacuolar H(+)-transporting ATPase 116 kDa subunit, a1 isoform
- ATPase, H+ transporting, lysosomal V0 subunit a1b
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