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AXL Produits

(AXL Receptor tyrosine Kinase (AXL))

Catégories

The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Catégories AXL en vedette

AXL Anticorps

High quality antibodies with extensive validation data.

AXL Kits ELISA

Reliable ELISA kits for a wide range of species.

AXL Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

AXL recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (1)
  • (6)
N° du produit ABIN560017
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (5)
N° du produit ABIN7265804
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (4)
N° du produit ABIN7265803
Quantité 100 μL
Fiche technique Fiche technique

AXL recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954023
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954024
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
N° du produit ABIN624944
Quantité 96 tests
Fiche technique Fiche technique

AXL recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7273881
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7273880
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN6961128
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits AXL

Novoyatleva, Rai, Kojonazarov, Veeroju, Ben-Batalla, Caruso, Shihan, Presser, Götz, Lepper, Herpel, Manaud, Perros, Gall, Ghofrani, Weissmann, Grimminger, Wharton, Wilkins, Upton, Loges, Morrell et al.: "Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2. ..." dans: Communications biology, Vol. 4, Issue 1, pp. 1002, (2021) (PubMed).

Dumas, Naudin, Martin-Lannerée, Izac, Casetti, Mansier, Rousseau, Artus, Dufossée, Giese, Dubus, Pigneux, Praloran, Bidet, Villacreces, Guitart, Milpied, Kosmider, Vigon, Desplat, Dusanter-Fourt et al.: "Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5- and hypoxia- dependent up-regulation of AXL. ..." dans: Haematologica, (2019) (PubMed).

Zapatero-Belinchón, Dietzel, Dolnik, Döhner, Costa, Hertel, Veselkova, Kirui, Klintworth, Manns, Pöhlmann, Pietschmann, Krey, Ciesek, Gerold, Sodeik, Becker, von Hahn: "Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors." dans: Viruses, Vol. 11, Issue 3, (2019) (PubMed).

Kasikara, Davra, Calianese, Geng, Spires, Quigley, Wichroski, Sriram, Suarez-Lopez, Yaffe, Kotenko, De Lorenzo, Birge: "Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer." dans: Cancer research, Vol. 79, Issue 10, pp. 2669-2683, (2019) (PubMed).

Sinik, Minson, Tentler, Carrico, Bagby, Robinson, Kami, Burstyn-Cohen, Eckhardt, Wang, Frye, Earp, DeRyckere, Graham: "Inhibition of MERTK Promotes Suppression of Tumor Growth in BRAF Mutant and BRAF Wild-Type Melanoma." dans: Molecular cancer therapeutics, Vol. 18, Issue 2, pp. 278-288, (2019) (PubMed).

Mills, Quinn, Roach, Palisoul, Nguyen, Noia, Guo, Fazal, Mutch, Wickline, Pan, Fuh: "p5RHH nanoparticle-mediated delivery of AXL siRNA inhibits metastasis of ovarian and uterine cancer cells in mouse xenografts." dans: Scientific reports, Vol. 9, Issue 1, pp. 4762, (2019) (PubMed).

Santamaria-Barria, Zeng, Greer, Beckman, Seifert, Cohen, Zhang, Crawley, Green, Loo, Maltbaek, DeMatteo: "Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells." dans: PLoS ONE, Vol. 14, Issue 5, pp. e0216275, (2019) (PubMed).

Jardine, Wiscombe, Reynolds, McDonald, Fuller, Green, Filby, Forrest, Ruchaud-Sparagano, Scott, Collin, Haniffa, Simpson: "Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace." dans: Nature communications, Vol. 10, Issue 1, pp. 1999, (2019) (PubMed).

Strange, Jiyarom, Pourhabibi Zarandi, Xie, Baker, Sadri-Ardekani, Shi, Verma: "Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells." dans: mBio, Vol. 10, Issue 4, (2019) (PubMed).

Carestia, Mena, Olexen, Ortiz Wilczyñski, Negrotto, Errasti, Gómez, Jenne, Carrera Silva, Schattner: "Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice." dans: Cell reports, Vol. 28, Issue 4, pp. 896-908.e5, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à AXL

AXL receptor tyrosine kinase (AXL), AXL receptor tyrosine kinase (Axl), Axl receptor tyrosine kinase (Axl), AI323647, Ark, JTK11, Tyro7, UFO, Ufo

Protein level used designations for AXL

  • AXL oncogene
  • AXL transforming sequence/gene
  • tyrosine-protein kinase receptor UFO
  • adhesion-related kinase
  • ufo oncogene homolog
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