BAI1 Produits
(Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
Catégories
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008].
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Catégories BAI1 en vedette
BAI1 Anticorps
High quality antibodies with extensive validation data.
BAI1 Kits ELISA
Reliable ELISA kits for a wide range of species.
BAI1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BAI1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (4)
N° du produit
ABIN392804
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (3)
N° du produit
ABIN3181614
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC, WB, ELISA, IF, ICC
Validations
- (3)
N° du produit
ABIN6257957
Quantité
100 μL
Fiche technique
Fiche technique
BAI1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954184
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4881934
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6385397
Quantité
96 tests
Fiche technique
Fiche technique
BAI1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7413106
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
N° du produit
ABIN6964229
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN6121439
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits BAI1
: "BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation." dans: Cancer cell, Vol. 33, Issue 6, pp. 1004-1016.e5, (2018) (PubMed).: "Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion." dans: Nature, Vol. 497, Issue 7448, pp. 263-7, (2013) (PubMed).
: "Antiangiogenic activity of BAI1 in vivo: implications for gene therapy of human glioblastomas." dans: Cancer gene therapy, Vol. 13, Issue 4, pp. 385-92, (2006) (PubMed).
: "Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression." dans: The American journal of pathology, Vol. 162, Issue 1, pp. 19-27, (2002) (PubMed).
: "Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis." dans: British journal of cancer, Vol. 86, Issue 3, pp. 490-6, (2002) (PubMed).
: "Brain-specific angiogenesis inhibitor 1 (BAI1) is expressed in human cerebral neuronal cells." dans: Neuroscience research, Vol. 43, Issue 1, pp. 69-74, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à BAI1
brain-specific angiogenesis inhibitor 1 (BAI1), adhesion G protein-coupled receptor B1 (ADGRB1), brain-specific angiogenesis inhibitor 1 (LOC100228084), adhesion G protein-coupled receptor B1 (Adgrb1), B830018M07Rik, BAI1, GDAIF, mKIAA4089, R75078Protein level used designations for BAI1
- brain-specific angiogenesis inhibitor 1
- brain-specific angiogenesis inhibitor 1-like
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