BAK1 Produits
(BCL2-Antagonist/killer 1 (BAK1))
Catégories
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008].
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Catégories BAK1 en vedette
BAK1 Anticorps
High quality antibodies with extensive validation data.
BAK1 Kits ELISA
Reliable ELISA kits for a wide range of species.
BAK1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BAK1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC, Neut
Validations
- (6)
N° du produit
ABIN5611250
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IP
Validations
- (8)
N° du produit
ABIN3020677
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (2)
- (10)
N° du produit
ABIN3042342
Quantité
100 μg
Fiche technique
Fiche technique
BAK1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965129
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965130
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954055
Quantité
96 tests
Fiche technique
Fiche technique
BAK1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1346390
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1346392
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7396205
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits BAK1
: "YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo-/radio-resistance by suppressing caspase-mediated apoptosis." dans: The Journal of pathology, (2019) (PubMed).: "Copper induces oxidative stress and apoptosis through mitochondria-mediated pathway in chicken hepatocytes." dans: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 54, pp. 310-316, (2019) (PubMed).
: "MicroRNA-29c Correlates with Neuroprotection Induced by FNS by Targeting Both Birc2 and Bak1 in Rat Brain after Stroke." dans: CNS neuroscience & therapeutics, Vol. 21, Issue 6, pp. 496-503, (2016) (PubMed).
: "Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability." dans: Molecular neurobiology, (2015) (PubMed).
: "Ovatodiolide sensitizes aggressive breast cancer cells to doxorubicin, eliminates their cancer stem cell-like phenotype, and reduces doxorubicin-associated toxicity." dans: Cancer letters, Vol. 364, Issue 2, pp. 125-34, (2015) (PubMed).
: "Notch4 Signaling Confers Susceptibility to TRAIL-Induced Apoptosis in Breast Cancer Cells." dans: Journal of cellular biochemistry, Vol. 116, Issue 7, pp. 1371-80, (2015) (PubMed).
: "Regulation of cell transformation by Rb-controlled redox homeostasis." dans: PLoS ONE, Vol. 9, Issue 7, pp. e102582, (2014) (PubMed).
: "The C-terminal domain (CTD) in linker histones antagonizes anti-apoptotic proteins to modulate apoptotic outcomes at the mitochondrion." dans: Cell death & disease, Vol. 5, pp. e1058, (2014) (PubMed).
: "Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy." dans: Cancer research, Vol. 73, Issue 2, pp. 519-28, (2013) (PubMed).
: "Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells." dans: Cell death and differentiation, Vol. 19, Issue 12, pp. 1928-38, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à BAK1
BCL2 antagonist/killer 1 (BAK1), BCL2-antagonist/killer 1 (Bak1), BCL2 antagonist/killer 1 (Bak1), BCL2 antagonist/killer 1 L homeolog (bak1.L), BAK, Bak, bak, BAK-LIKE, Bak1, bak1, BCL2L7, CDN1, N-Bak, N-BAK1Protein level used designations for BAK1
- BCL2-like 7 protein
- apoptosis regulator BAK
- bcl-2 homologous antagonist/killer
- bcl-2-like protein 7
- bcl2-L-7
- pro-apoptotic protein BAK
- Bcl2 homologous antagonist/killer
- Bcl-2-like 7
- BCL2 antagonist/killer 1 L homeolog
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