BCAM Produits
(Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))
Catégories
This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
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Catégories BCAM en vedette
BCAM Anticorps
High quality antibodies with extensive validation data.
BCAM Kits ELISA
Reliable ELISA kits for a wide range of species.
BCAM Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BCAM recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (6)
N° du produit
ABIN7442009
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (6)
N° du produit
ABIN7193338
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7145263
Quantité
100 μg
Fiche technique
Fiche technique
BCAM recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954046
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN5510708
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN625265
Quantité
96 tests
Fiche technique
Fiche technique
BCAM recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7273932
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7273935
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7273931
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits BCAM
: "An Anti-Human Lutheran Glycoprotein Phage Antibody Inhibits Cell Migration on Laminin-511: Epitope Mapping of the Antibody." dans: PLoS ONE, Vol. 12, Issue 1, pp. e0167860, (2017) (PubMed).: "BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS-Mutant Colorectal Cancer." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 19, pp. 4923-4933, (2016) (PubMed).
: "Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation." dans: The Journal of biological chemistry, Vol. 289, Issue 16, pp. 11512-21, (2014) (PubMed).
: "The lutheran/basal cell adhesion molecule promotes tumor cell migration by modulating integrin-mediated cell attachment to laminin-511 protein." dans: The Journal of biological chemistry, Vol. 288, Issue 43, pp. 30990-1001, (2013) (PubMed).
: "An antibody to the lutheran glycoprotein (Lu) recognizing the LU4 blood type variant inhibits cell adhesion to laminin α5." dans: PLoS ONE, Vol. 6, Issue 8, pp. e23329, (2011) (PubMed).
: "Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of ..." dans: Journal of bacteriology, Vol. 189, Issue 11, pp. 3977-86, (2007) (PubMed).
: "A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane." dans: Blood, Vol. 101, Issue 10, pp. 4180-8, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à BCAM
basal cell adhesion molecule (Lutheran blood group) (bcam), basal cell adhesion molecule (Lutheran blood group) L homeolog (bcam.L), basal cell adhesion molecule (Lutheran blood group) (BCAM), basal cell adhesion molecule (BCAM), basal cell adhesion molecule (Bcam), basal cell adhesion molecule (Lutheran blood group) (Bcam), 1200005K12Rik, AU, B-CAM, cd239, CD239, Gplu, LU, Lu, MGC81012, msk19, MSK19, prr2, zgc:154034Protein level used designations for BCAM
- basal cell adhesion molecule (Lutheran blood group)
- Auberger b antigen
- Lutheran blood group
- basal cell adhesion molecule (Lu and Au blood groups)
- basal cell adhesion molecule
- LU
- basal cell adhesion molecule-like
- B-CAM cell surface glycoprotein
- lutheran antigen
- lutheran glycoprotein
- B-cell adhesion molecule
- F8/G253 antigen
- antigen identified by monoclonal antibody F8
- glycoprotein 95kDa
- Lutheran blood group (Auberger b antigen included)
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