BCAR3 Produits
(Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
Catégories
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
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Catégories BCAR3 en vedette
BCAR3 Anticorps
High quality antibodies with extensive validation data.
BCAR3 Kits ELISA
Reliable ELISA kits for a wide range of species.
BCAR3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BCAR3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
N° du produit
ABIN6260215
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
N° du produit
ABIN6257959
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
N° du produit
ABIN563616
Quantité
100 μg
Fiche technique
Fiche technique
BCAR3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965237
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954192
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5648159
Quantité
96 tests
Fiche technique
Fiche technique
BCAR3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1346502
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7414060
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2715176
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits BCAR3
: "Protein tyrosine phosphatase α phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions." dans: Molecular and cellular biology, Vol. 32, Issue 18, pp. 3776-89, (2012) (PubMed).: "Breast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane ruffling." dans: Cancer research, Vol. 67, Issue 13, pp. 6174-82, (2007) (PubMed).
: "Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells." dans: The EMBO journal, Vol. 17, Issue 10, pp. 2799-808, (1998) (PubMed).
Synonymes et noms alternatifs relatifs à BCAR3
breast cancer anti-estrogen resistance 3 (BCAR3), breast cancer anti-estrogen resistance 3 (Bcar3), breast cancer anti-estrogen resistance 3 (bcar3), breast cancer anti-estrogen resistance 3 L homeolog (bcar3.L), AI131758, AND-34, BCAR3, NSP2, SH2D3BProtein level used designations for BCAR3
- SH2 domain-containing protein 3B
- breast cancer anti-estrogen resistance protein 3
- breast cancer antiestrogen resistance 3 protein
- dJ1033H22.2 (breast cancer anti-estrogen resistance 3)
- novel SH2-containing protein 2
- p130Cas-binding protein AND-34
- breast cancer anti-estrogen resistance 3
- breast cancer antiestrogen resistance 3
- breast cancer anti-estrogen resistance protein 3-like
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