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BCAT1 Produits

(Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1))

Catégories

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010].

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Catégories BCAT1 en vedette

BCAT1 Anticorps

High quality antibodies with extensive validation data.

BCAT1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BCAT1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7445063
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7445177
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7445060
Quantité 100 μL
Fiche technique Fiche technique

BCAT1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6227409
Quantité 96 tests
Fiche technique Fiche technique

BCAT1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122027
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346515
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7419871
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits BCAT1

Li, Ye, Xie, Hua, Yang, Wu, Gu, Ren, Mao: "Defect of branched-chain amino acid metabolism promotes the development of Alzheimer's disease by targeting the mTOR signaling." dans: Bioscience reports, Vol. 38, Issue 4, (2018) (PubMed).

Cho, Jeon, Park, Park, Kang, Choi: "BCAT1 is a New MR Imaging-related Biomarker for Prognosis Prediction in IDH1-wildtype Glioblastoma Patients." dans: Scientific reports, Vol. 7, Issue 1, pp. 17740, (2017) (PubMed).

Hattori, Tsunoda, Konuma, Kobayashi, Nagy, Glushka, Tayyari, McSkimming, Kannan, Tojo, Edison, Ito: "Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia." dans: Nature, Vol. 545, Issue 7655, pp. 500-504, (2017) (PubMed).

Petersen, Reddien: "Smed-betacatenin-1 is required for anteroposterior blastema polarity in planarian regeneration." dans: Science (New York, N.Y.), Vol. 319, Issue 5861, pp. 327-30, (2008) (PubMed).

Nakatani, Thompson, Barthel, Sakaue, Liu, Weigel, Roth: "Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines." dans: The Journal of biological chemistry, Vol. 274, Issue 31, pp. 21528-32, (1999) (PubMed).

Ben-Yosef, Yanuka, Halle, Benvenisty: "Involvement of Myc targets in c-myc and N-myc induced human tumors." dans: Oncogene, Vol. 17, Issue 2, pp. 165-71, (1998) (PubMed).

Frech, Andjelkovic, Ingley, Reddy, Falck, Hemmings: "High affinity binding of inositol phosphates and phosphoinositides to the pleckstrin homology domain of RAC/protein kinase B and their influence on kinase activity." dans: The Journal of biological chemistry, Vol. 272, Issue 13, pp. 8474-81, (1997) (PubMed).

Ben-Yosef, Yanuka, Benvenisty: "ECA39 is regulated by c-Myc in human and by a Jun/Fos homolog, Gcn4, in yeast." dans: Oncogene, Vol. 13, Issue 9, pp. 1859-66, (1997) (PubMed).

Cross, Alessi, Cohen, Andjelkovich, Hemmings: "Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B." dans: Nature, Vol. 378, Issue 6559, pp. 785-9, (1996) (PubMed).

Eden, Simchen, Benvenisty: "Two yeast homologs of ECA39, a target for c-Myc regulation, code for cytosolic and mitochondrial branched-chain amino acid aminotransferases." dans: The Journal of biological chemistry, Vol. 271, Issue 34, pp. 20242-5, (1996) (PubMed).

Synonymes et noms alternatifs relatifs à BCAT1

branched chain amino-acid transaminase 1, cytosolic (bcat1), branched chain amino acid transaminase 1 (BCAT1), branched chain amino-acid transaminase 1, cytosolic L homeolog (bcat1.L), branched chain aminotransferase 1, cytosolic (bcat1), branched chain amino acid transaminase 1 (bcat1), branched chain amino acid transaminase 1 (Bcat1), branched chain aminotransferase 1, cytosolic (Bcat1), Bcatc, BCATC, BCATc, BCT1, ECA39, Eca39, fj66g02, MECA39, PNAS121, PP18, wu:fj66g02, zgc:73157

Protein level used designations for BCAT1

  • branched-chain-amino-acid aminotransferase, cytosolic
  • branched chain aminotransferase 1, cytosolic
  • branched chain amino-acid transaminase 1, cytosolic
  • branched-chain-amino-acid aminotransferase, cytosolic-like
  • BCAT(c)
  • placental protein 18
  • cytosolic branched-chain amino acid aminotransferase
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