BCL10 Produits
(B-Cell CLL/lymphoma 10 (BCL10))
Catégories
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008].
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Catégories BCL10 en vedette
BCL10 Anticorps
High quality antibodies with extensive validation data.
BCL10 Kits ELISA
Reliable ELISA kits for a wide range of species.
BCL10 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BCL10 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
- (4)
N° du produit
ABIN1944800
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (2)
- (4)
N° du produit
ABIN1724629
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, FACS, IHC (p)
Validations
- (4)
N° du produit
ABIN654655
Quantité
400 μL
Fiche technique
Fiche technique
BCL10 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965103
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962056
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4881949
Quantité
96 tests
Fiche technique
Fiche technique
BCL10 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1346536
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN2128105
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7417939
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits BCL10
: "Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent." dans: Inflammatory bowel diseases, Vol. 16, Issue 4, pp. 593-603, (2010) (PubMed).: "Toll-like receptor 4 mediates induction of the Bcl10-NFkappaB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cells." dans: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10550-8, (2008) (PubMed).
: "Development, evaluation, and application of a highly sensitive microtiter plate ELISA for human Bcl10 protein." dans: Journal of immunoassay & immunochemistry, Vol. 28, Issue 3, pp. 173-88, (2007) (PubMed).
: "A preferential role for STAT5, not constitutively active STAT3, in promoting survival of a human lymphoid tumor." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 8, pp. 5032-40, (2006) (PubMed).
: "MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression." dans: The Journal of pathology, Vol. 205, Issue 3, pp. 293-301, (2005) (PubMed).
: "Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells." dans: Nature immunology, Vol. 4, Issue 9, pp. 857-65, (2003) (PubMed).
: "Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B." dans: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21405-9, (2001) (PubMed).
: "Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway." dans: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19012-9, (2001) (PubMed).
: "BCL10 expression in normal and neoplastic lymphoid tissue. Nuclear localization in MALT lymphoma." dans: The American journal of pathology, Vol. 157, Issue 4, pp. 1147-54, (2000) (PubMed).
: "BCL10 gene mutation in lymphoma." dans: Blood, Vol. 95, Issue 12, pp. 3885-90, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à BCL10
B-cell CLL/lymphoma 10 (BCL10), B-cell CLL/lymphoma 10 (Bcl10), B-cell CLL/lymphoma 10 (bcl10), B-cell lymphoma/leukemia 10-like (LOC100223183), B cell leukemia/lymphoma 10 (Bcl10), B-cell lymphoma/leukemia 10 (bcl10), AI132454, BCL-10, BCL10, bcl10, c-E10, C81403, CARMEN, cE10, CIPER, CLAP, mE10, ME10Protein level used designations for BCL10
- B-cell lymphoma/leukemia 10
- CARD containing molecule enhancing NF-kB
- CARD-containing apoptotic signaling protein
- CARD-containing molecule enhancing NF-kappa-B
- CARD-containing proapoptotic protein
- CED-3/ICH-1 prodomain homologous E10-like regulator
- cCARMEN
- caspase-recruiting domain-containing protein
- cellular homolog of vCARMEN
- cellular-E10
- hCLAP
- mammalian CARD-containing adapter molecule E10
- B-cell leukemia/lymphoma 10
- R-RCD1
- RCD
- bcl-10
- B-cell lymophoma 10 protein
- B-cell CLL/lymphoma 10
- B cell lymphoma/leukemia 10
- CARD-like apoptotic protein
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