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BCL10 Produits

(B-Cell CLL/lymphoma 10 (BCL10))
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008].

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Catégories BCL10 en vedette

BCL10 Anticorps

High quality antibodies with extensive validation data.

BCL10 Kits ELISA

Reliable ELISA kits for a wide range of species.

BCL10 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BCL10 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
  • (4)
N° du produit ABIN1944800
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (2)
  • (4)
N° du produit ABIN1724629
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IF, FACS, IHC (p)
Validations
  • (4)
N° du produit ABIN654655
Quantité 400 μL
Fiche technique Fiche technique

BCL10 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965103
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962056
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4881949
Quantité 96 tests
Fiche technique Fiche technique

BCL10 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346536
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2128105
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7417939
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits BCL10

Borthakur, Bhattacharyya, Alrefai, Tobacman, Ramaswamy, Dudeja: "Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent." dans: Inflammatory bowel diseases, Vol. 16, Issue 4, pp. 593-603, (2010) (PubMed).

Bhattacharyya, Gill, Chen, Zhang, Linhardt, Dudeja, Tobacman: "Toll-like receptor 4 mediates induction of the Bcl10-NFkappaB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cells." dans: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10550-8, (2008) (PubMed).

Bhattacharyya, Pant, Dudeja, Tobacman: "Development, evaluation, and application of a highly sensitive microtiter plate ELISA for human Bcl10 protein." dans: Journal of immunoassay & immunochemistry, Vol. 28, Issue 3, pp. 173-88, (2007) (PubMed).

Nagy, Rui, Stepkowski, Karras, Kirken: "A preferential role for STAT5, not constitutively active STAT3, in promoting survival of a human lymphoid tumor." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 8, pp. 5032-40, (2006) (PubMed).

Ye, Gong, Liu, Hamoudi, Shirali, Ho, Chott, Streubel, Siebert, Gesk, Martin-Subero, Radford, Banerjee, Nicholson, Ranaldi, Remstein, Gao, Zheng, Isaacson, Dogan, Du: "MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression." dans: The Journal of pathology, Vol. 205, Issue 3, pp. 293-301, (2005) (PubMed).

Xue, Morris, Orihuela, Tuomanen, Cui, Wen, Wang: "Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells." dans: Nature immunology, Vol. 4, Issue 9, pp. 857-65, (2003) (PubMed).

Wang, Guo, Huang, Ke, Poyet, Manji, Merriam, Glucksmann, DiStefano, Alnemri, Bertin: "Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B." dans: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21405-9, (2001) (PubMed).

Lucas, Yonezumi, Inohara, McAllister-Lucas, Abazeed, Chen, Yamaoka, Seto, Nunez: "Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway." dans: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19012-9, (2001) (PubMed).

Ye, Dogan, Karran, Willis, Chen, Wlodarska, Dyer, Isaacson, Du: "BCL10 expression in normal and neoplastic lymphoid tissue. Nuclear localization in MALT lymphoma." dans: The American journal of pathology, Vol. 157, Issue 4, pp. 1147-54, (2000) (PubMed).

Du, Peng, Liu, Hamoudi, Diss, Willis, Ye, Dogan, Wotherspoon, Dyer, Isaacson: "BCL10 gene mutation in lymphoma." dans: Blood, Vol. 95, Issue 12, pp. 3885-90, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à BCL10

B-cell CLL/lymphoma 10 (BCL10), B-cell CLL/lymphoma 10 (Bcl10), B-cell CLL/lymphoma 10 (bcl10), B-cell lymphoma/leukemia 10-like (LOC100223183), B cell leukemia/lymphoma 10 (Bcl10), B-cell lymphoma/leukemia 10 (bcl10), AI132454, BCL-10, BCL10, bcl10, c-E10, C81403, CARMEN, cE10, CIPER, CLAP, mE10, ME10

Protein level used designations for BCL10

  • B-cell lymphoma/leukemia 10
  • CARD containing molecule enhancing NF-kB
  • CARD-containing apoptotic signaling protein
  • CARD-containing molecule enhancing NF-kappa-B
  • CARD-containing proapoptotic protein
  • CED-3/ICH-1 prodomain homologous E10-like regulator
  • cCARMEN
  • caspase-recruiting domain-containing protein
  • cellular homolog of vCARMEN
  • cellular-E10
  • hCLAP
  • mammalian CARD-containing adapter molecule E10
  • B-cell leukemia/lymphoma 10
  • R-RCD1
  • RCD
  • bcl-10
  • B-cell lymophoma 10 protein
  • B-cell CLL/lymphoma 10
  • B cell lymphoma/leukemia 10
  • CARD-like apoptotic protein
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