BCMA Produits
(Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
Catégories
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008].
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Catégories BCMA en vedette
BCMA Anticorps
High quality antibodies with extensive validation data.
BCMA Kits ELISA
Reliable ELISA kits for a wide range of species.
BCMA Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BCMA recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, FACS, IP, IF
Validations
- (5)
N° du produit
ABIN6961043
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (4)
N° du produit
ABIN7172255
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, IHC, IF
Validations
- (4)
N° du produit
ABIN7076067
Quantité
100 μL
Fiche technique
Fiche technique
BCMA recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970980
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6975649
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960291
Quantité
96 tests
Fiche technique
Fiche technique
BCMA recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7273940
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus, Rhesus Monkey
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7273936
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7273941
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits BCMA
: "Hypoxia Selectively Impairs CAR-T Cells In Vitro." dans: Cancers, Vol. 11, Issue 5, (2019) (PubMed).: "Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells." dans: Haematologica, (2019) (PubMed).
: "Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma. ..." dans: JCI insight, Vol. 3, Issue 8, (2018) (PubMed).
: "Pre-clinical validation of B cell maturation antigen (BCMA) as a target for T cell immunotherapy of multiple myeloma." dans: Oncotarget, Vol. 9, Issue 40, pp. 25764-25780, (2018) (PubMed).
: "CAR-T Cells Based on Novel BCMA Monoclonal Antibody Block Multiple Myeloma Cell Growth." dans: Cancers, Vol. 10, Issue 9, (2018) (PubMed).
: "Clinical relevance of circulating anti-ENA and anti-dsDNA secreting cells from SLE patients and their dependence on STAT-3 activation." dans: European journal of immunology, Vol. 47, Issue 7, pp. 1211-1219, (2017) (PubMed).
: "The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells." dans: Leukemia, Vol. 30, Issue 1, pp. 163-72, (2016) (PubMed).
: "γ-Secretase directly sheds the survival receptor BCMA from plasma cells." dans: Nature communications, Vol. 6, pp. 7333, (2015) (PubMed).
: "The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 2, pp. 542-52, (2015) (PubMed).
: "PD-L1hi B cells are critical regulators of humoral immunity." dans: Nature communications, Vol. 6, pp. 5997, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à BCMA
TNF receptor superfamily member 17 (Tnfrsf17), TNF receptor superfamily member 17 (TNFRSF17), tumor necrosis factor receptor superfamily, member 17 (Tnfrsf17), BCM, BCMA, CD269, Tnfrsf13, TNFRSF13A, Tnfrsf13a, TNFRSF17Protein level used designations for BCMA
- tumor necrosis factor receptor superfamily member 17
- tumor necrosis factor receptor superfamily, member 17
- B cell maturation antigen
- B-cell maturation factor
- B-cell maturation protein
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