BIK Produits
(BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
Catégories
The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011].
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Catégories BIK en vedette
BIK Anticorps
High quality antibodies with extensive validation data.
BIK Kits ELISA
Reliable ELISA kits for a wide range of species.
BIK Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BIK recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, ELISA, IF, ICC
Validations
- (5)
N° du produit
ABIN6260261
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), FACS
Validations
- (6)
N° du produit
ABIN4950330
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (3)
N° du produit
ABIN388114
Quantité
400 μL
Fiche technique
Fiche technique
BIK recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380102
Quantité
2 x 96 tests
Fiche technique
Fiche technique
BIK recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1346675
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1346677
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3131975
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits BIK
: "β-arrestin-2 enhances intestinal epithelial apoptosis in necrotizing enterocolitis." dans: Aging, Vol. 11, Issue 19, pp. 8294-8312, (2019) (PubMed).: "Methotrexate upregulates circadian transcriptional factors PAR bZIP to induce apoptosis on rheumatoid arthritis synovial fibroblasts." dans: Arthritis research & therapy, Vol. 20, Issue 1, pp. 55, (2018) (PubMed).
: "Targeting SQSTM1/p62 induces cargo loading failure and converts autophagy to apoptosis via NBK/Bik." dans: Molecular and cellular biology, Vol. 34, Issue 18, pp. 3435-49, (2014) (PubMed).
: "Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity." dans: Blood, Vol. 109, Issue 10, pp. 4360-7, (2007) (PubMed).
: "TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 10, pp. 7042-9, (2007) (PubMed).
: "The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through ..." dans: The Journal of biological chemistry, Vol. 281, Issue 35, pp. 25850-66, (2006) (PubMed).
: "Transcriptional activation of the proapoptotic bik gene by E2F proteins in cancer cells." dans: FEBS letters, Vol. 580, Issue 25, pp. 5905-9, (2006) (PubMed).
: "Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis." dans: The EMBO journal, Vol. 24, Issue 8, pp. 1546-56, (2005) (PubMed).
: "BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death." dans: The Journal of biological chemistry, Vol. 280, Issue 25, pp. 23829-36, (2005) (PubMed).
: "BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria." dans: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 18053-60, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à BIK
BCL2 interacting killer (BIK), BCL2-interacting killer (Bik), BCL2-interacting killer (apoptosis-inducing) (bik), BIK, Biklk, BIP1, Blk, BP4, Nbk, NBK, si:dkey-31f5.6Protein level used designations for BIK
- BCL2-interacting killer (apoptosis-inducing)
- BCL2-interacting killer
- apoptosis inducer NBK
- bcl-2-interacting killer
- bik-like killer protein
- apoptosis-inducing NBK
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