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BLK Produits

(B Lymphoid Tyrosine Kinase (BLK))

Catégories

This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010].

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Catégories BLK en vedette

BLK Anticorps

High quality antibodies with extensive validation data.

BLK Kits ELISA

Reliable ELISA kits for a wide range of species.

BLK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BLK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro), ICC
Validations
  • (6)
N° du produit ABIN7441157
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (5)
N° du produit ABIN560064
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
N° du produit ABIN392087
Quantité 400 μL
Fiche technique Fiche technique

BLK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954026
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN4885999
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951074
Quantité 96 tests
Fiche technique Fiche technique

BLK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346711
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346709
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121957
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits BLK

Bernal-Quirós, Wu, Alarcón-Riquelme, Castillejo-López: "BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling." dans: PLoS ONE, Vol. 8, Issue 3, pp. e59842, (2013) (PubMed).

Chen, Felix, Wang: "Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 5684-92, (2011) (PubMed).

Castillejo-López, Delgado-Vega, Wojcik, Kozyrev, Thavathiru, Wu, Sánchez, Pöllmann, López-Egido, Fineschi, Domínguez, Lu, James, Merrill, Kelly, Kaufman, Moser, Gilkeson, Frostegård, Pons-Estel et al.: "Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK. ..." dans: Annals of the rheumatic diseases, Vol. 71, Issue 1, pp. 136-42, (2011) (PubMed).

Yang, Ng, Zhao, Hirankarn, Lau, Mok, Chan, Wong, Lee, Mok, Wong, Avihingsanon, Lee, Ho, Lee, Wong, Lau: "Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese." dans: Genes and immunity, Vol. 10, Issue 3, pp. 219-26, (2009) (PubMed).

Borowiec, Liew, Thompson, Boonyasrisawat, Hu, Mlynarski, El Khattabi, Kim, Marselli, Rich, Krolewski, Bonner-Weir, Sharma, Sale, Mychaleckyj, Kulkarni, Doria: "Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 34, pp. 14460-5, (2009) (PubMed).

Hom, Graham, Modrek, Taylor, Ortmann, Garnier, Lee, Chung, Ferreira, Pant, Ballinger, Kosoy, Demirci, Kamboh, Kao, Tian, Gunnarsson, Bengtsson, Rantapää-Dahlqvist, Petri, Manzi, Seldin, Rönnblom et al.: "Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. ..." dans: The New England journal of medicine, Vol. 358, Issue 9, pp. 900-9, (2008) (PubMed).

Chen, Huang, Wang: "Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity." dans: Blood, Vol. 109, Issue 10, pp. 4360-7, (2007) (PubMed).

Tretter, Ross, Dordai, Desiderio: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." dans: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à BLK

BLK proto-oncogene, Src family tyrosine kinase (blk), BLK proto-oncogene, Src family tyrosine kinase (BLK), B lymphoid kinase (Blk), BLK proto-oncogene, Src family tyrosine kinase (Blk), bltk, MODY11, si:dkey-33i22.2, zgc:136231

Protein level used designations for BLK

  • B lymphoid kinase
  • tyrosine-protein kinase Blk
  • B lymphoid tyrosine kinase
  • tyrosine-protein kinase Blk-like
  • b lymphocyte kinase
  • p55-Blk
  • BLK nonreceptor tyrosine kinase
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