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BLM Produits

(Bloom Syndrome RecQ Like Helicase (BLM))
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq, Jul 2008].

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Catégories BLM en vedette

BLM Anticorps

High quality antibodies with extensive validation data.

BLM Kits ELISA

Reliable ELISA kits for a wide range of species.

BLM Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BLM recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IF, IHC (p), ICC
Validations
  • (4)
N° du produit ABIN2855003
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
N° du produit ABIN7138888
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS
Validations
  • (2)
N° du produit ABIN651053
Quantité 400 μL
Fiche technique Fiche technique

BLM recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1123945
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1123947
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method
Validations
N° du produit ABIN1123946
Quantité 96 tests
Fiche technique Fiche technique

BLM recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346713
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3089946
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3132191
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits BLM

Yoshimura: "Increased error-free DNA repair gene expression through reprogramming in human iPS cells." dans: Regenerative therapy, Vol. 11, pp. 101-105, (2019) (PubMed).

Nicholls, Nadalutti, Motori, Sommerville, Gorman, Basu, Hoberg, Turnbull, Chinnery, Larsson, Larsson, Falkenberg, Taylor, Griffith, Gustafsson: "Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA." dans: Molecular cell, Vol. 69, Issue 1, pp. 9-23.e6, (2018) (PubMed).

Arora, Abdel-Fatah, Agarwal, Doherty, Moseley, Aleskandarany, Green, Ball, Alshareeda, Rakha, Chan, Ellis, Madhusudan: "Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer." dans: Molecular cancer therapeutics, Vol. 14, Issue 4, pp. 1057-65, (2015) (PubMed).

Meena, Cerutti, Beichler, Morita, Bruhn, Kumar, Kraus, Speicher, Wang, Kestler, dAdda di Fagagna, Günes, Rudolph: "Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion." dans: The EMBO journal, Vol. 34, Issue 10, pp. 1371-84, (2015) (PubMed).

Murfuni, Nicolai, Baldari, Crescenzi, Bignami, Franchitto, Pichierri: "The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation." dans: Oncogene, Vol. 32, Issue 5, pp. 610-20, (2013) (PubMed).

Lao, Welcsh, Luo, Carter, Dzieciatkowski, Dintzis, Meza, Sarvetnick, Monnat, Loeb, Grady: "Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers." dans: Translational oncology, Vol. 6, Issue 4, pp. 458-69, (2013) (PubMed).

Srivastava, Modi, Tripathi, Mudgal, De, Sengupta: "BLM helicase stimulates the ATPase and chromatin-remodeling activities of RAD54." dans: Journal of cell science, Vol. 122, Issue Pt 17, pp. 3093-103, (2009) (PubMed).

Nair, Emmons, Cress, Argilagos, Lam, Kerr, Wang, Dalton, Hazlehurst: "HYD1-induced increase in reactive oxygen species leads to autophagy and necrotic cell death in multiple myeloma cells." dans: Molecular cancer therapeutics, Vol. 8, Issue 8, pp. 2441-51, (2009) (PubMed).

Shimura, Torres, Martin, Rao, Pommier, Katsura, Miyagawa, Aladjem: "Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress." dans: Journal of molecular biology, Vol. 375, Issue 4, pp. 1152-64, (2008) (PubMed).

Tripathi, Nagarjuna, Sengupta: "BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination." dans: The Journal of cell biology, Vol. 178, Issue 1, pp. 9-14, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à BLM

Bloom syndrome RecQ like helicase (BLM), Bloom syndrome RecQ like helicase S homeolog (blm.S), Bloom syndrome RecQ like helicase (Blm), Bloom syndrome, RecQ like helicase (Blm), blm-A, BS, ORF1, RECQ2, RECQL2, RECQL3, xBLM

Protein level used designations for BLM

  • Bloom syndrome protein
  • DNA helicase, RecQ-like type 2
  • recQ protein-like 3
  • Bloom syndrome, RecQ helicase-like
  • Bloom syndrome protein homolog
  • recQ helicase homolog
  • BLM helicase
  • Gd BLM
  • Bloom syndrome homolog
  • mBLM
  • Bloom syndrome protein-like
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