Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

BMX Produits

(BMX Non-Receptor Tyrosine Kinase (BMX))
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories BMX en vedette

BMX Anticorps

High quality antibodies with extensive validation data.

BMX Kits ELISA

Reliable ELISA kits for a wide range of species.

BMX Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BMX recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (4)
N° du produit ABIN7443482
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
N° du produit ABIN6261616
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (3)
N° du produit ABIN7184420
Quantité 100 μL
Fiche technique Fiche technique

BMX recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965180
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954117
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5691925
Quantité 2 x 96 tests
Fiche technique Fiche technique

BMX recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346793
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN2715316
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Rat
Source Insect Cells
Validations
N° du produit ABIN5509204
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits BMX

Fox, Storey: "BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs." dans: Cancer research, Vol. 75, Issue 7, pp. 1345-55, (2015) (PubMed).

Chakrabarti, Davidge: "Estradiol modulates tumor necrosis factor-induced endothelial inflammation: role of tumor necrosis factor receptor 2." dans: Journal of vascular research, Vol. 50, Issue 1, pp. 21-34, (2012) (PubMed).

Gottar-Guillier, Dodeller, Huesken, Iourgenko, Mickanin, Labow, Gaveriaux, Kinzel, Mueller, Alitalo, Littlewood-Evans, Cenni: "The tyrosine kinase BMX is an essential mediator of inflammatory arthritis in a kinase-independent manner." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 10, pp. 6014-23, (2011) (PubMed).

Palmer, Mutch, Workman, McDaid, Horwood, Foxwell: "Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity." dans: Blood, Vol. 111, Issue 4, pp. 1781-8, (2008) (PubMed).

Tu, Thotala, Geng, Hallahan, Willey: "Bone marrow X kinase-mediated signal transduction in irradiated vascular endothelium." dans: Cancer research, Vol. 68, Issue 8, pp. 2861-9, (2008) (PubMed).

Côté, Motoyama, Bush, Vuori: "A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling." dans: Nature cell biology, Vol. 7, Issue 8, pp. 797-807, (2005) (PubMed).

Nore, Mattsson, Antonsson, Bäckesjö, Westlund, Lennartsson, Hansson, Löw, Rönnstrand, Smith: "Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases." dans: Biochimica et biophysica acta, Vol. 1645, Issue 2, pp. 123-32, (2003) (PubMed).

Vargas, Nore, Berglof, Heinonen, Mattsson, Smith, Mohamed: "Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx." dans: The Journal of biological chemistry, Vol. 277, Issue 11, pp. 9351-7, (2002) (PubMed).

Yang, Kim, Wu, Qiu: "Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking." dans: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 30219-26, (2002) (PubMed).

Pan, An, Zhang, He, Yin, Min: "Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesis." dans: Molecular and cellular biology, Vol. 22, Issue 21, pp. 7512-23, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à BMX

BMX non-receptor tyrosine kinase (BMX), BMX non-receptor tyrosine kinase (bmx), BMX non-receptor tyrosine kinase (Bmx), BMX, ETK, Etk, Etk/Bmx, PSCTK2, PSCTK3, RGD1565643, Tyro8

Protein level used designations for BMX

  • BMX non-receptor tyrosine kinase
  • cytoplasmic tyrosine-protein kinase BMX-like
  • BTK-like on X chromosome
  • Etk/Bmx cytosolic tyrosine kinase
  • NTK38 tyrosine kinase
  • bone marrow tyrosine kinase gene in chromosome X protein
  • cytoplasmic tyrosine-protein kinase BMX
  • epithelial and endothelial tyrosine kinase
  • TYRO8 protein tyrosine kinase 8
  • bone marrow tyrosine kinase gene in chromosome X protein homolog
Vous êtes ici:
Support technique