BRD4 Produits
(Bromodomain Containing 4 (BRD4))
Catégories
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15\;19)(q13\;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
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Catégories BRD4 en vedette
BRD4 Anticorps
High quality antibodies with extensive validation data.
BRD4 Kits ELISA
Reliable ELISA kits for a wide range of species.
BRD4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BRD4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
N° du produit
ABIN7010051
Quantité
60 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (4)
N° du produit
ABIN6137653
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
N° du produit
ABIN6260309
Quantité
100 μL
Fiche technique
Fiche technique
BRD4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965241
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954198
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1124204
Quantité
96 tests
Fiche technique
Fiche technique
BRD4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122050
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7319875
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN6964231
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits BRD4
: "BRD4 regulates fructose-inducible lipid accumulation-related genes in the mouse liver." dans: Metabolism: clinical and experimental, Vol. 65, Issue 10, pp. 1478-88, (2017) (PubMed).: "H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs." dans: Cell reports, Vol. 14, Issue 5, pp. 1142-55, (2016) (PubMed).
: "Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils." dans: Nature communications, Vol. 6, pp. 6061, (2015) (PubMed).
: "The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains." dans: Genes & development, Vol. 29, Issue 14, pp. 1507-23, (2015) (PubMed).
: "The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors." dans: PLoS ONE, Vol. 8, Issue 6, pp. e64880, (2013) (PubMed).
: "The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3." dans: Molecular and cellular biology, Vol. 31, Issue 13, pp. 2641-52, (2011) (PubMed).
: "RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia." dans: Nature, Vol. 478, Issue 7370, pp. 524-8, (2011) (PubMed).
: "Targeting MYC dependence in cancer by inhibiting BET bromodomains." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 40, pp. 16669-74, (2011) (PubMed).
: "NCoR1 mediates papillomavirus E8;E2C transcriptional repression." dans: Journal of virology, Vol. 84, Issue 9, pp. 4451-60, (2010) (PubMed).
: "Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4." dans: Journal of virology, Vol. 83, Issue 9, pp. 4127-39, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à BRD4
bromodomain containing 4 L homeolog (brd4.L), bromodomain containing 4 (BRD4), bromodomain containing 4 (brd4), bromodomain-containing protein 4 (LOC100409351), bromodomain containing 4 (Brd4), BRD4, brd4-b, Brd5, CAP, fb18g03, HUNK1, HUNKI, MCAP, WI-11513, wu:fb18g03Protein level used designations for BRD4
- Bromodomain-containing protein 4B
- bromodomain-containing protein 4B
- bromodomain containing 4
- bromodomain-containing protein 4
- bromodomain 4
- bromodomain-containing protein 4-like
- bromodomain containing protein 4
- bromodomain-containing 4
- chromosome-associated protein
- bromodomain-containing 5
- fsh-like protein
- mitotic chromosome-associated protein
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