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BRMS1 Produits

(Breast Cancer Metastasis Suppressor 1 (BRMS1))

Catégories

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Catégories BRMS1 en vedette

BRMS1 Anticorps

High quality antibodies with extensive validation data.

BRMS1 Kits ELISA

Reliable ELISA kits for a wide range of species.

BRMS1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BRMS1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IP
Validations
  • (8)
  • (5)
N° du produit ABIN565191
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN7265929
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (3)
N° du produit ABIN6256973
Quantité 100 μL
Fiche technique Fiche technique

BRMS1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6202158
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method
Validations
N° du produit ABIN1124133
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6202159
Quantité 96 tests
Fiche technique Fiche technique

BRMS1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346875
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2128213
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3090160
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits BRMS1

Ventura, Quezada, Maloney, Fernandes, Antecka, Martins, Bakalian, di Cesare, Burnier: "Expression of the metastasis suppressor BRMS1 in uveal melanoma." dans: Ecancermedicalscience, Vol. 8, pp. 410, (2014) (PubMed).

Liu, Mayo, Nagji, Hall, Shock, Xiao, Stelow, Jones: "BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300." dans: Cancer research, Vol. 73, Issue 4, pp. 1308-17, (2013) (PubMed).

Cui, Liu, He, Li, Huang, Sun, Tang, Chen, Jiang, Chen, Yun, Zeng, Guo, Wang, Ma: "Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival." dans: BMC cancer, Vol. 12, pp. 376, (2012) (PubMed).

Kim, Nam, Pyo, Jang, Kim, Kim, Boo, Lee, Yoon, Baek, Kim: "Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex." dans: Biochemical and biophysical research communications, Vol. 415, Issue 4, pp. 720-6, (2011) (PubMed).

Nagji, Liu, Stelow, Stukenborg, Jones: "BRMS1 transcriptional repression correlates with CpG island methylation and advanced pathological stage in non-small cell lung cancer." dans: The Journal of pathology, Vol. 221, Issue 2, pp. 229-37, (2010) (PubMed).

Wu, McEwen, Harihar, Baker, DeWald, Zhou: "BRMS1 expression alters the ultrastructural, biomechanical and biochemical properties of MDA-MB-435 human breast carcinoma cells: an AFM and Raman microspectroscopy study." dans: Cancer letters, Vol. 293, Issue 1, pp. 82-91, (2010) (PubMed).

Smith, Liu, Siefert, Moskaluk, Petroni, Jones: "Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis and correlates with improved patient survival in non-small cell lung cancer." dans: Cancer letters, Vol. 276, Issue 2, pp. 196-203, (2009) (PubMed).

Vaidya, Sanchez, Kim, Welch: "Expression of the Breast Cancer Metastasis Suppressor 1 (BRMS1) maintains in vitro chemosensitivity of breast cancer cells." dans: Cancer letters, Vol. 281, Issue 1, pp. 100-7, (2009) (PubMed).

Frolova, Edmonds, Bodenstine, Seitz, Johnson, Feng, Welch, Frost: "A shift from nuclear to cytoplasmic breast cancer metastasis suppressor 1 expression is associated with highly proliferative estrogen receptor-negative breast cancers." dans: Tumour biology, Vol. 30, Issue 3, pp. 148-59, (2009) (PubMed).

Cicek, Fukuyama, Cicek, Sizemore, Welch, Sizemore, Casey: "BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-kappaB binding site of the uPA promoter." dans: Clinical & experimental metastasis, Vol. 26, Issue 3, pp. 229-37, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à BRMS1

breast cancer metastasis suppressor 1 (BRMS1), breast cancer metastasis-suppressor 1 (Brms1), breast cancer metastasis suppressor 1 L homeolog (brms1.L), breast cancer metastasis suppressor 1 (Brms1), breast cancer metastasis suppressor 1 (brms1), AV003220, AW554636, BRMS1, BRMS1L, MGC98869, si:zc188c22.3, si:zc194c5.2, wu:fb57b08, zgc:56414

Protein level used designations for BRMS1

  • breast cancer metastasis-suppressor 1
  • breast cancer metastasis suppressor 1
  • breast cancer metastasis-suppressor 1 homolog
  • breast cancer metastasis-suppressor 1-like protein
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