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BTK Produits

(Bruton Agammaglobulinemia tyrosine Kinase (BTK))
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq, Nov 2008].

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Catégories BTK en vedette

BTK Anticorps

High quality antibodies with extensive validation data.

BTK Kits ELISA

Reliable ELISA kits for a wide range of species.

BTK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BTK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (5)
N° du produit ABIN3022171
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
N° du produit ABIN7265950
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (5)
N° du produit ABIN3030207
Quantité 0.4 mL
Fiche technique Fiche technique

BTK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (3)
N° du produit ABIN1981713
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965243
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965242
Quantité 96 tests
Fiche technique Fiche technique

BTK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346956
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346958
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7491289
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits BTK

Yu, Bondada, Ghoshal, Singh, Pistilli, Dayaram, Iqbal, Sands, Davis, Bondada, Geddes: "Repositioning Flubendazole for Spinal Cord Injury." dans: Journal of neurotrauma, (2019) (PubMed).

Liu, Zhang, Han, Wang, Liu, Zhang, Zhou, Xiang: "Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." dans: Molecular medicine reports, Vol. 16, Issue 1, pp. 192-200, (2017) (PubMed).

Hoshino, Okuno, Migita, Ban, Yang, Kiyokawa, Adachi, Kojima, Ohara, Kanegane: "X-linked agammaglobulinemia associated with B-precursor acute lymphoblastic leukemia." dans: Journal of clinical immunology, Vol. 35, Issue 2, pp. 108-11, (2015) (PubMed).

Wang, Iwata, Nakayamada, Niiro, Jabbarzadeh-Tabrizi, Kondo, Kubo, Yoshikawa, Tanaka: "Amplification of IL-21 signalling pathway through Bruton's tyrosine kinase in human B cell activation." dans: Rheumatology (Oxford, England), Vol. 54, Issue 8, pp. 1488-97, (2015) (PubMed).

Guo, Liu, Bhardwaj, Yang, Changou, Ma, Mazloom, Chintapalli, Xiao, Xiao, Kumaresan, Sanchez, Yeh, Evans, Patterson, Lam, Kung: "Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor." dans: Cell death & disease, Vol. 5, pp. e1409, (2014) (PubMed).

Eda, Santo, Cirstea, Yee, Scullen, Nemani, Mishima, Waterman, Arastu-Kapur, Evans, Singh, Kirk, Westlin, Raje et al.: "A novel Bruton's tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma ..." dans: Leukemia, Vol. 28, Issue 9, pp. 1892-901, (2014) (PubMed).

Gleixner, Peter, Blatt, Suppan, Reiter, Radia, Hadzijusufovic, Valent: "Synergistic growth-inhibitory effects of ponatinib and midostaurin (PKC412) on neoplastic mast cells carrying KIT D816V." dans: Haematologica, Vol. 98, Issue 9, pp. 1450-7, (2013) (PubMed).

Krupa, Fudala, Florence, Tucker, Allen, Standiford, Luchowski, Fol, Rahman, Gryczynski, Gryczynski, Kurdowska: "Bruton's tyrosine kinase mediates FcγRIIa/Toll-like receptor-4 receptor crosstalk in human neutrophils." dans: American journal of respiratory cell and molecular biology, Vol. 48, Issue 2, pp. 240-9, (2013) (PubMed).

Lindvall, Blomberg, Väliaho, Vargas, Heinonen, Berglöf, Mohamed, Nore, Vihinen, Smith: "Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling." dans: Immunological reviews, Vol. 203, pp. 200-15, (2005) (PubMed).

Schimmer: "Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice." dans: Cancer research, Vol. 64, Issue 20, pp. 7183-90, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à BTK

Bruton tyrosine kinase (BTK), Bruton agammaglobulinemia tyrosine kinase (btk), Bruton tyrosine kinase (btk), Bruton agammaglobulinemia tyrosine kinase (Btk), Bruton tyrosine kinase (Btk), agmx1, AGMX1, AI528679, AT, atk, ATK, bpk, BPK, BTK, imd1, IMD1, psctk1, PSCTK1, xid, xla, XLA

Protein level used designations for BTK

  • Bruton agammaglobulinemia tyrosine kinase
  • B-cell progenitor kinase
  • agammaglobulinaemia tyrosine kinase
  • dominant-negative kinase-deficient Brutons tyrosine kinase
  • tyrosine-protein kinase BTK
  • tyrosine-protein kinase BTK isoform (lacking exon 14)
  • ATK
  • BPK
  • Bruton's tyrosine kinase
  • Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB)
  • X-linked immune deficiency
  • agammaglobulinemia tyrosine kinase
  • bruton tyrosine kinase
  • kinase EMB
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