CACNA1A Produits
(Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))
Catégories
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits polymorphic variation due to (CAG)n-repeats. Multiple transcript variants encoding different isoforms have been found for this gene. In one set of transcript variants, the (CAG)n-repeats occur in the 3' UTR, and are not associated with any disease. But in another set of variants, an insertion extends the coding region to include the (CAG)n-repeats which encode a polyglutamine tract. Expansion of the (CAG)n-repeats from the normal 4-16 to 21-28 in the coding region is associated with spinocerebellar ataxia 6. [provided by RefSeq, Mar 2010].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories CACNA1A en vedette
CACNA1A Anticorps
High quality antibodies with extensive validation data.
CACNA1A Kits ELISA
Reliable ELISA kits for a wide range of species.
CACNA1A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
N° du produit
ABIN7175608
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB
Validations
- (1)
N° du produit
ABIN306878
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (1)
N° du produit
ABIN6243080
Quantité
200 μL
Fiche technique
Fiche technique
CACNA1A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965321
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965320
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1167089
Quantité
96 tests
Fiche technique
Fiche technique
Dernières publications sur nos produits CACNA1A
: "The Cav2.1/alpha1A (P/Q-type) voltage-dependent calcium channel mediates inhibitory neurotransmission onto mouse cerebellar Purkinje cells." dans: The European journal of neuroscience, Vol. 13, Issue 10, pp. 1902-12, (2001) (PubMed).: "Vascular smooth muscle cells express the alpha(1A) subunit of a P-/Q-type voltage-dependent Ca(2+)Channel, and It is functionally important in renal afferent arterioles." dans: Circulation research, Vol. 87, Issue 10, pp. 896-902, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit S homeolog (cacna1a.S), calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a (cacna1aa), calcium voltage-gated channel subunit alpha1 A (CACNA1A), calcium voltage-gated channel subunit alpha1 A (Cacna1a), calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (Cacna1a), P/Q-type voltage-gated calcium channel alpha1A subunit ChCaChA1A (LOC395892), alpha1A, APCA, BccA1, BI, ca(v)2.1, Caca1a, CACH4, CACN3, cacna-a, cacna1a, CACNL1A4, Cacnl1a4, cav2.1, Cav2.1, CAV2.1, Ccha1a, EA2, FHM, HPCA, la, leaner, MHP, MHP1, nmf352, rbA-1, rkr, rocker, SCA6, si:ch211-237k17.1, tg, totteringProtein level used designations for CACNA1A
- calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
- voltage-dependent calcium ion channel alpha subunit
- ZfCav2.1
- BI
- RBA-I
- brain calcium channel 1
- brain calcium channel I
- brain class A
- calcium channel alpha 1A
- calcium channel, L type, alpha-1 polypeptide
- calcium channel, voltage-dependent, alpha 1A subunit
- voltage-dependent P/Q-type calcium channel subunit alpha-1A
- voltage-gated calcium channel subunit alpha Cav2.1
- P/Q-type calcium channel alpha1A subunit
- calcium channel, P/Q type, alpha 1A
- calcium channel, alpha 1A subunit
- voltage-gated calcium channel alpha 1A subunit
- calcium channel BI-1
- calcium channel BI-2
Vous êtes ici:
