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CACNA1G Produits

(Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))

Catégories

Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011].

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Catégories CACNA1G en vedette

CACNA1G Anticorps

High quality antibodies with extensive validation data.

CACNA1G recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN680608
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN1027719
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN2483303
Quantité 100 μg
Fiche technique Fiche technique

CACNA1G recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6213224
Quantité 96 tests
Fiche technique Fiche technique

Dernières publications sur nos produits CACNA1G

Curran, Musa, Kline, Makara, Little, Higgins, Hund, Band, Mohler: "Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria." dans: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12210-21, (2015) (PubMed).

Lu, Long, Zhou, Xu, Hu, Li: "Mibefradil reduces blood glucose concentration in db/db mice." dans: Clinics (São Paulo, Brazil), Vol. 69, Issue 1, pp. 61-7, (2014) (PubMed).

Borahay, Kilic, Yallampalli, Snyder, Hankins, Al-Hendy, Boehning: "Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells." dans: The Journal of biological chemistry, Vol. 289, Issue 51, pp. 35075-86, (2014) (PubMed).

Rice, Berchtold, Cotman, Green: "Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production." dans: Neurobiology of aging, Vol. 35, Issue 5, pp. 1002-11, (2014) (PubMed).

Valerie, Dziegielewska, Hosing, Augustin, Gray, Brautigan, Larner, Dziegielewski: "Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells." dans: Biochemical pharmacology, Vol. 85, Issue 7, pp. 888-97, (2013) (PubMed).

Puthussery, Venkataramani, Gayet-Primo, Smith, Taylor: "NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 41, pp. 16045-59, (2013) (PubMed).

Strandberg, Cui, Rath, Liu, Silverman, Liu, Siragam, Ackerley, Su, Yan, Capecchi, Biavati, Accorroni, Yuen, Quattrone, Lung, Jaeggi, Backx, Deber, Hamilton: "Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts." dans: PLoS ONE, Vol. 8, Issue 9, pp. e72668, (2013) (PubMed).

Goonasekera, Hammer, Auger-Messier, Bodi, Chen, Zhang, Reiken, Elrod, Correll, York, Sargent, Hofmann, Moosmang, Marks, Houser, Bers, Molkentin: "Decreased cardiac L-type Ca²? channel activity induces hypertrophy and heart failure in mice." dans: The Journal of clinical investigation, Vol. 122, Issue 1, pp. 280-90, (2012) (PubMed).

Ernst, Zhang, Yoo, Ernst, Noebels: "Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 6, pp. 1615-25, (2009) (PubMed).

Sohal, Huguenard: "It takes T to tango." dans: Neuron, Vol. 31, Issue 1, pp. 3-4, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à CACNA1G

calcium voltage-gated channel subunit alpha1 G (CACNA1G), calcium channel, voltage-dependent, T type, alpha 1G subunit (cacna1g), calcium channel, voltage-dependent, T type, alpha 1G subunit L homeolog (cacna1g.L), calcium channel, voltage-dependent, T type, alpha 1G subunit (Cacna1g), calcium voltage-gated channel subunit alpha1 G (Cacna1g), a1G, alpha-1G, ca(v)3.1, Ca(v)3.1, Ca(V)T.1, CACNA1G, cav3.1, Cav3.1, Cav3.1d, mKIAA1123, NBR13, [a]1G

Protein level used designations for CACNA1G

  • voltage-dependent calcium channel alpha 1G subunit
  • calcium channel, voltage-dependent, T type, alpha 1G subunit
  • calcium channel voltage-dependent T type Cav3.1, alpha 1g subunit
  • cav3.1c
  • voltage-dependent T-type calcium channel subunit alpha-1G
  • voltage-gated calcium channel subunit alpha Cav3.1
  • calcium channel, voltage-dependent, alpha 1G subunit
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