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CAD Produits

(Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))

Catégories

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. [provided by RefSeq, Jul 2008].

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Catégories CAD en vedette

CAD Anticorps

High quality antibodies with extensive validation data.

CAD recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (7)
N° du produit ABIN655062
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, WB, IF
Validations
  • (8)
N° du produit ABIN7264367
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, WB, IF
Validations
  • (6)
N° du produit ABIN6137837
Quantité 100 μL
Fiche technique Fiche technique

CAD recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122124
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CAD

Morin, Fritsch, Mathieu, Gilbert, Guarmit, Firlej, Gallou-Kabani, Vieillefond, Delongchamps, Cabon: "Identification of CAD as an androgen receptor interactant and an early marker of prostate tumor recurrence." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 1, pp. 460-7, (2012) (PubMed).

Huang, Bell, Okamura, Kim, Mohney, Guerrero-Preston, Ratovitski: "Phospho-ΔNp63α/SREBF1 protein interactions: bridging cell metabolism and cisplatin chemoresistance." dans: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 20, pp. 3810-27, (2012) (PubMed).

Watanabe, Inai, Jinnouchi, Baba, Yagi: "Expression of caspase-activated deoxyribonuclease (CAD) and caspase 3 (CPP32) in the cochlea of cisplatin (CDDP)-treated guinea pigs." dans: Auris, nasus, larynx, Vol. 30, Issue 3, pp. 219-25, (2003) (PubMed).

Watanabe, Tomiyama, Jinnouchi, Yagi: "Expression of caspase-activated deoxyribonuclease (CAD) and caspase 3 (CPP32) in the hydropic cochlea of guinea pigs - second report." dans: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, Vol. 259, Issue 5, pp. 257-61, (2002) (PubMed).

Hara, Miyake, Arakawa, Kamidono, Hara: "Over expression of inhibitor of caspase 3 activated deoxyribonuclease in human renal cell carcinoma cells enhances their resistance to cytotoxic chemotherapy in vivo." dans: The Journal of urology, Vol. 166, Issue 6, pp. 2491-4, (2001) (PubMed).

Schneider, Thome, Burns, Bodmer, Hofmann, Kataoka, Holler, Tschopp: "TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB." dans: Immunity, Vol. 7, Issue 6, pp. 831-6, (1998) (PubMed).

Synonymes et noms alternatifs relatifs à CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD), carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (Cad), carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (cad), 2410008J01Rik, AU018859, CAD, cb456, Cpad, si:dkey-221h15.3, wu:fc30c12, wu:fc33d01, wu:fc67g02, xcad

Protein level used designations for CAD

  • CAD protein
  • CAD trifunctional protein
  • multifunctional protein CAD
  • carbamyl phosphatate synthetase 2
  • carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase
  • carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • CAD protein-like
  • CAD protein carbamylphosphate synthetase domain
  • dihydrorotate synthase
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