Cadherin 4 Produits
(Cadherin 4 (CDH4))
Catégories
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
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Catégories Cadherin 4 en vedette
Cadherin 4 Anticorps
High quality antibodies with extensive validation data.
Cadherin 4 Kits ELISA
Reliable ELISA kits for a wide range of species.
Cadherin 4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Cadherin 4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, FACS, IHC (p)
Validations
- (1)
- (5)
N° du produit
ABIN388148
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
WB, IHC, IP
Validations
- (3)
- (3)
N° du produit
ABIN967954
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, FACS, IHC (p), EIA
Validations
- (4)
N° du produit
ABIN356865
Quantité
0.4 mL
Fiche technique
Fiche technique
Cadherin 4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6730333
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4882287
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6385128
Quantité
96 tests
Fiche technique
Fiche technique
Cadherin 4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348916
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7403762
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
N° du produit
ABIN7317950
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Cadherin 4
: "Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning." dans: Nature neuroscience, Vol. 20, Issue 4, pp. 540-549, (2017) (PubMed).: "Chronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective Cells." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0130561, (2015) (PubMed).
: "Delineation of the key aspects in the regulation of epithelial monolayer formation." dans: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2535-50, (2013) (PubMed).
: "Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells." dans: Cancer letters, Vol. 297, Issue 2, pp. 198-206, (2010) (PubMed).
: "R-cadherin influences cell motility via Rho family GTPases." dans: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31041-9, (2004) (PubMed).
: "Frequent aberrant methylation of the CDH4 gene promoter in human colorectal and gastric cancer." dans: Cancer research, Vol. 64, Issue 22, pp. 8156-9, (2004) (PubMed).
: "Mutation analysis of cadherin-4 reveals amino acid residues of EC1 important for the structure and function." dans: Biochemical and biophysical research communications, Vol. 271, Issue 2, pp. 358-63, (2000) (PubMed).
: "Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin." dans: Cell adhesion and communication, Vol. 2, Issue 1, pp. 15-26, (1995) (PubMed).
: "Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue." dans: Molecular endocrinology (Baltimore, Md.), Vol. 7, Issue 9, pp. 1151-60, (1994) (PubMed).
: "Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene." dans: Journal of cell science, Vol. 106 ( Pt 1), Issue 6, pp. 401-9, (1994) (PubMed).
Synonymes et noms alternatifs relatifs à Cadherin 4
cadherin 4 (cdh4), cadherin 4 (Cdh4), cadherin 4, type 1, R-cadherin (retinal) (cdh4), cadherin 4 (CDH4), Cadherin-4 (cdh-4), AW120700, cad4, CAD4, cadherin-4, Cdh4l, R-Cadh, R-cadherin, rcad, Rcad, RCAD, zgc:136316Protein level used designations for Cadherin 4
- cadherin 4, type 1, R-cadherin (retinal)
- R-CAD
- cadherin-4
- retina cadherin
- retinal cadherin
- R-cadherin
- cadherin 4 type 1 R-cadherin (retinal)
- cadherin 4, type 1, preproprotein
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