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Camello-Like 2 Protein (CML2)

CML2 Origine: Humain Hôte: Mammalian Cells Synthetic Nanodisc
N° du produit ABIN7538157
  • Antigène
    Camello-Like 2 (CML2)
    Type de proteíne
    Synthetic Nanodisc
    Origine
    Humain
    Source
    Mammalian Cells
    Fonction
    Human CML2 full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    Camello-Like 2 (CML2)
    Autre désignation
    CML2
    Synonymes
    RGD1561619 Protein, N-acetyltransferase 8 (GCN5-related) family member 2 Protein, camello-like 2 Protein, Nat8f2 Protein, Cml2 Protein
    Sujet
    Receptor for the inflammation-associated leukocyte chemoattractant chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation (PubMed:18165312). Receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway (By similarity).[UniProtKB/Swiss-Prot Function]
    Poids moléculaire
    The human full length CML2 protein has a MW of 41.4kDa
    UniProt
    P46091
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