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CARD11 Produits

(Caspase Recruitment Domain Family, Member 11 (CARD11))

Catégories

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008].

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Catégories CARD11 en vedette

CARD11 Anticorps

High quality antibodies with extensive validation data.

CARD11 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CARD11 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN7266125
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (2)
N° du produit ABIN7263125
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (2)
N° du produit ABIN6260459
Quantité 100 μL
Fiche technique Fiche technique

CARD11 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6202319
Quantité 96 tests
Fiche technique Fiche technique

CARD11 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1348037
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3090358
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3136496
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CARD11

Gu, Sun: "MiR-539 inhibits thyroid cancer cell migration and invasion by directly targeting CARMA1." dans: Biochemical and biophysical research communications, Vol. 464, Issue 4, pp. 1128-33, (2015) (PubMed).

Cheng, Hamilton, Kane: "Phosphorylation of Carma1, but not Bcl10, by Akt regulates TCR/CD28-mediated NF-κB induction and cytokine production." dans: Molecular immunology, Vol. 59, Issue 1, pp. 110-6, (2014) (PubMed).

Hamilton, Phong, Corey, Cheng, Gorentla, Zhong, Shiva, Kane: "T cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10." dans: Science signaling, Vol. 7, Issue 329, pp. ra55, (2014) (PubMed).

Rajasekaran, Kumar, Schuldt, Peterson, Vanhaesebroeck, Dixit, Thakar, Malarkannan: "Signaling by Fyn-ADAP via the Carma1-Bcl-10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells." dans: Nature immunology, Vol. 14, Issue 11, pp. 1127-36, (2013) (PubMed).

Moreno-García, Sommer, Shinohara, Bandaranayake, Kurosaki, Rawlings: "MAGUK-controlled ubiquitination of CARMA1 modulates lymphocyte NF-kappaB activity." dans: Molecular and cellular biology, Vol. 30, Issue 4, pp. 922-34, (2010) (PubMed).

Rueda, Gaide, Ho, Lewkowicz, Niedergang, Hailfinger, Rebeaud, Guzzardi, Conne, Thelen, Delon, Ferch, Mak, Ruland, Schwaller, Thome: "Bcl10 controls TCR- and FcgammaR-induced actin polymerization." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 7, pp. 4373-84, (2007) (PubMed).

Medeiros, Burbach, Mueller, Srivastava, Moon, Highfill, Peterson, Shimizu: "Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1." dans: Science (New York, N.Y.), Vol. 316, Issue 5825, pp. 754-8, (2007) (PubMed).

Ho, Davis, Conne, Chappuis, Berczy, Mhawech, Staudt, Schwaller: "MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-kappa B-dependent proliferative advantage and resistance against FAS-induced cell death in B cells." dans: Blood, Vol. 105, Issue 7, pp. 2891-9, (2005) (PubMed).

Sommer, Guo, Pomerantz, Bandaranayake, Moreno-García, Ovechkina, Rawlings: "Phosphorylation of the CARMA1 linker controls NF-kappaB activation." dans: Immunity, Vol. 23, Issue 6, pp. 561-74, (2005) (PubMed).

Nakamura, Nakamura, Matsumoto, Yada, Hirahashi, Suekane, Yao, Goda, Iida: "Overexpression of caspase recruitment domain (CARD) membrane-associated guanylate kinase 1 (CARMA1) and CARD9 in primary gastric B-cell lymphoma." dans: Cancer, Vol. 104, Issue 9, pp. 1885-93, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à CARD11

caspase recruitment domain family member 11 (CARD11), caspase recruitment domain family, member 11 (Card11), caspase recruitment domain-containing protein 11 (LOC100550812), caspase recruitment domain family member 11 (card11), caspase recruitment domain family member 11 (Card11), 0610008L17Rik, 2410011D02Rik, BENTA, BIMP3, CARD11, CARMA1, LOC100232755, PPBL

Protein level used designations for CARD11

  • CARD-containing MAGUK protein 1
  • bcl10-interacting maguk protein 3
  • carma 1
  • caspase recruitment domain-containing protein 11
  • caspase recruitment domain family, member 11
  • caspase recruitment domain-containing protein 11-like
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