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Cathepsin L1 Produits

(Cathepsin L1 (CTSL1))

Catégories

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012].

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Catégories Cathepsin L1 en vedette

Cathepsin L1 Anticorps

High quality antibodies with extensive validation data.

Cathepsin L1 Kits ELISA

Reliable ELISA kits for a wide range of species.

Cathepsin L1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Cathepsin L1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (1)
  • (6)
N° du produit ABIN7431587
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Pig, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (5)
N° du produit ABIN687532
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7239770
Quantité 200 μL
Fiche technique Fiche technique

Cathepsin L1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6954461
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6954463
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962834
Quantité 96 tests
Fiche technique Fiche technique

Cathepsin L1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122182
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350727
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350725
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Cathepsin L1

Zhang, Wei, Li, He, Liu, Deng, Cheng, Du, Liu, Chen, Sun, Yu, Fu: "COVID-19 receptor and malignant cancers: Association of CTSL expression with susceptibility to SARS-CoV-2." dans: International journal of biological sciences, Vol. 18, Issue 6, pp. 2362-2371, (2022) (PubMed).

Yeow, Kotamraju, Wang, Chopra, Azme, Wu, Schoep, Delaney, Feindel, Li, Kennedy, Allen, Kennedy, Larma, Sampson, Mahakian, Fite, Zhang, Friman, Mann, Aziz, Kumarasinghe, Johansson, Ee, Yeoh, Mou et al.: "Immune-mediated ECM depletion improves tumour perfusion and payload delivery. ..." dans: EMBO molecular medicine, Vol. 11, Issue 12, pp. e10923, (2020) (PubMed).

Hernáez, Guerra, Salas, Andrés: "African Swine Fever Virus Undergoes Outer Envelope Disruption, Capsid Disassembly and Inner Envelope Fusion before Core Release from Multivesicular Endosomes." dans: PLoS pathogens, Vol. 12, Issue 4, pp. e1005595, (2016) (PubMed).

Sudhan, Pampo, Rice, Siemann: "Cathepsin L inactivation leads to multimodal inhibition of prostate cancer cell dissemination in a preclinical bone metastasis model." dans: International journal of cancer, Vol. 138, Issue 11, pp. 2665-77, (2016) (PubMed).

Liu, Xu, Ye, Liang, Wu, Zheng, Deng, Li, Liu: "Urinary proteins induce lysosomal membrane permeabilization and lysosomal dysfunction in renal tubular epithelial cells." dans: American journal of physiology. Renal physiology, Vol. 308, Issue 6, pp. F639-49, (2015) (PubMed).

Tholen, Wolanski, Stolze, Chiabudini, Gajda, Bronsert, Stickeler, Rospert, Reinheckel: "Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression." dans: The Journal of biological chemistry, Vol. 290, Issue 25, pp. 15758-69, (2015) (PubMed).

Kim, Woo, Kim, Jang, Hwang, Kwon, Choi, Kim, Cheng, Jin, Kim, Kim, Kim: "Biochemical and clinical correlation of intraplaque neovascularization using contrast-enhanced ultrasound of the carotid artery." dans: Atherosclerosis, Vol. 233, Issue 2, pp. 579-83, (2014) (PubMed).

Baldzizhar, Fedorchuk, Jha, Rathinam, Henegariu, Czyzyk: "Anti-serpin antibody-mediated regulation of proteases in autoimmune diabetes." dans: The Journal of biological chemistry, Vol. 288, Issue 3, pp. 1612-9, (2013) (PubMed).

Capoccia, Jin, Kong, Peek, Fassan, Rugge, Mills: "The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation." dans: The Journal of clinical investigation, Vol. 123, Issue 4, pp. 1475-91, (2013) (PubMed).

García, Kohen, Maldonado, Sierralta, Muñoz, Villarroel, Strauss, Devoto: "Transient expression of progesterone receptor and cathepsin-l in human granulosa cells during the periovulatory period." dans: Fertility and sterility, Vol. 97, Issue 3, pp. 707-13.e1, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à Cathepsin L1

cathepsin L (CTSL), cathepsin L (Ctsl), cathepsin V (CTSV), cathepsin L L homeolog (ctsl.L), cathepsin L (ctsl), cathepsin L1 (LOC100008830), Cathepsin L1 (catl1), cathepsin L (26-29-p), Cathepsin L (catl), cathepsin L1 (Tsp_11596), testin gene (Testin), cathepsin 12 (cts12), cathepsin L1 (LOC102156614), cathepsin Lb (ctslb), cathepsin L.1 (ctsl.1), 26-29-p, 1190035F06Rik, CATHL, CATL, CatL, catl, catL, cb15, Cp1, cpl-1, Ctsl, CTSL, ctsl, CTSL1, Ctsl1, ctsl1b, CTSV, fs, hgg1, LOC663234, MEP, mep, MGC80629, MGC107932, nkt, si:dkey-121a11.6, wu:fb30g09, zgc:92089

Protein level used designations for Cathepsin L1

  • cathepsin L1
  • major excreted protein
  • Cat L
  • furless
  • nackt
  • p39 cysteine proteinase
  • CP-2
  • MEP
  • cathepsin L
  • cyclic protein 2
  • Cathepsin L1
  • cathepsin L1-like
  • 26-29kD-proteinase
  • cysteine proteinase-1
  • Cathepsin L
  • CMB-23
  • testin-2
  • cathepsin V
  • cathepsin L, 1 b
  • cathepsin L, b
  • cathepsin Lb
  • cstlb
  • hatching gland 1
  • hatching gland gene 1
  • cathepsin L.1
  • ctslc
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