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C-Type Lectin Domain Family 6, Member A Produits

(C-Type Lectin Domain Family 6, Member A (CLEC6A))
Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functionnal receptor for alpha-mannans on C. albicans hypheas. Plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. Recognizes also, in a manose dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptative immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway.

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Catégories C-Type Lectin Domain Family 6, Member A en vedette

C-Type Lectin Domain Family 6, Member A Anticorps

High quality antibodies with extensive validation data.

C-Type Lectin Domain Family 6, Member A Kits ELISA

Reliable ELISA kits for a wide range of species.

C-Type Lectin Domain Family 6, Member A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

C-Type Lectin Domain Family 6, Member A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7186528
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, FACS, IHC (p)
Validations
  • (3)
N° du produit ABIN959984
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (2)
N° du produit ABIN6260891
Quantité 100 μL
Fiche technique Fiche technique

C-Type Lectin Domain Family 6, Member A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730425
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4882590
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN6385418
Quantité 96 tests
Fiche technique Fiche technique

C-Type Lectin Domain Family 6, Member A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7320341
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
N° du produit ABIN2745635
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3115618
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits C-Type Lectin Domain Family 6, Member A

Botting, Bertram, Baharlou, Sandgren, Fletcher, Rhodes, Rana, Plasto, Wang, Lim, Barnouti, Kohout, Papadopoulos, Merten, Olbourne, Cunningham, Haniffa, Harman: "Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes." dans: Journal of leukocyte biology, Vol. 101, Issue 6, pp. 1393-1403, (2017) (PubMed).

Brasch, Mörig, Neumann, Proksch: "Expression of antimicrobial peptides and toll-like receptors is increased in tinea and pityriasis versicolor." dans: Mycoses, Vol. 57, Issue 3, pp. 147-52, (2014) (PubMed).

Barrett, Rahman, Fernandez, Parsons, Xing, Austen, Kanaoka: "Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes." dans: The Journal of experimental medicine, Vol. 208, Issue 3, pp. 593-604, (2011) (PubMed).

Gringhuis, Wevers, Kaptein, van Capel, Theelen, Boekhout, de Jong, Geijtenbeek: "Selective C-Rel activation via Malt1 controls anti-fungal T(H)-17 immunity by dectin-1 and dectin-2." dans: PLoS pathogens, Vol. 7, Issue 1, pp. e1001259, (2011) (PubMed).

Suram, Gangelhoff, Taylor, Rosas, Brown, Bonventre, Akira, Uematsu, Williams, Murphy, Leslie: "Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicans." dans: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30676-85, (2010) (PubMed).

Taylor, Reid, Heinsbroek, Brown, Gordon, Wong: "Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo." dans: European journal of immunology, Vol. 35, Issue 7, pp. 2163-74, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à C-Type Lectin Domain Family 6, Member A

C-type lectin domain containing 6A (CLEC6A), C-type lectin domain family 6, member A (Clec6a), CLEC4N, CLEC6A, CLECSF10

Protein level used designations for C-Type Lectin Domain Family 6, Member A

  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10
  • C-type lectin domain family 6 member A
  • C-type lectin superfamily member 10
  • DC-associated C-type lectin 2
  • dectin 2
  • dectin-2
  • dendritic cell-associated C-type lectin 2
  • C-type lectin domain family 6, member A
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