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C6 Produits

(Complement Component 6 (C6))
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012].

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Catégories C6 en vedette

C6 Anticorps

High quality antibodies with extensive validation data.

C6 Kits ELISA

Reliable ELISA kits for a wide range of species.

C6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

C6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7435277
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IF, IHC (p)
Validations
  • (1)
  • (4)
N° du produit ABIN390924
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA, FACS, IF
Validations
  • (7)
N° du produit ABIN3029693
Quantité 0.4 mL
Fiche technique Fiche technique

C6 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966018
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955020
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1440229
Quantité 96 tests
Fiche technique Fiche technique

C6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1776082
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
N° du produit ABIN7198986
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7397030
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits C6

Bettoni, Galbusera, Gastoldi, Donadelli, Tentori, Spartà, Bresin, Mele, Alberti, Tortajada, Yebenes, Remuzzi, Noris: "Interaction between Multimeric von Willebrand Factor and Complement: A Fresh Look to the Pathophysiology of Microvascular Thrombosis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 3, pp. 1021-1040, (2017) (PubMed).

Zhang, Li, Shan, Wang, Qiu, Lu, Zhao, Zhu, He, Wang: "Sublytic C5b-9 induces IL-6 and TGF-?1 production by glomerular mesangial cells in rat Thy-1 nephritis through p300-mediated C/EBP? acetylation." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 3, pp. 1511-25, (2014) (PubMed).

Orren: "Molecular mechanisms of complement component C6 deficiency; a hypervariable exon 6 region responsible for three of six reported defects." dans: Clinical and experimental immunology, Vol. 119, Issue 2, pp. 255-8, (2000) (PubMed).

Zhu, Atkinson, Hovanky, Boppana, Dai, Densen, Go, Jablecki, Volanakis: "High prevalence of complement component C6 deficiency among African-Americans in the south-eastern USA." dans: Clinical and experimental immunology, Vol. 119, Issue 2, pp. 305-10, (2000) (PubMed).

Sato, Van Dixhoorn, Prins, Mooney, Verhagen, Muizert, Savill, Van Es, Daha: "The terminal sequence of complement plays an essential role in antibody-mediated renal cell apoptosis." dans: Journal of the American Society of Nephrology : JASN, Vol. 10, Issue 6, pp. 1242-52, (1999) (PubMed).

Baker, Ochi, Schulze, Johnson, Campbell, Couser: "Depletion of C6 prevents development of proteinuria in experimental membranous nephropathy in rats." dans: The American journal of pathology, Vol. 135, Issue 1, pp. 185-94, (1989) (PubMed).

Schulze, Baker, Perkinson, Johnson, Ochi, Stahl, Couser: "Increased urinary excretion of C5b-9 distinguishes passive Heymann nephritis in the rat." dans: Kidney international, Vol. 35, Issue 1, pp. 60-8, (1989) (PubMed).

Synonymes et noms alternatifs relatifs à C6

complement component 6 (c6), complement C6 (C6), complement component 6, gene 1 L homeolog (c6.1.L), complement component 6, gene 2 (c6.2), complement component 6 (C6), AW111623, c6, C6, MGC82168, MGC89471, zgc:64073

Protein level used designations for C6

  • complement component C6
  • sixth complement component
  • complement component 6
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