CBFB Produits
(Core-Binding Factor, beta Subunit (CBFB))
Catégories
The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit\; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories CBFB en vedette
CBFB Anticorps
High quality antibodies with extensive validation data.
CBFB Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CBFB recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7444325
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, IHC (p), FACS
Validations
- (5)
N° du produit
ABIN390892
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, ChIP
Validations
- (6)
N° du produit
ABIN6655308
Quantité
100 μL
Fiche technique
Fiche technique
CBFB recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6951394
Quantité
96 tests
Fiche technique
Fiche technique
CBFB recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348166
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348164
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN2128359
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CBFB
: "Functions of Smad Transcription Factors in TGF-β1-Induced Selectin Ligand Expression on Murine CD4 Th Cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 7, pp. 2627-34, (2016) (PubMed).Synonymes et noms alternatifs relatifs à CBFB
core-binding factor beta subunit (CBFB), core binding factor beta subunit (Cbfb), core-binding factor, beta subunit (cbfb), core-binding factor, beta subunit (Cbfb), core-binding factor, beta subunit S homeolog (cbfb.S), core binding factor beta (Cbfb), core-binding factor beta subunit (Cbfb), AI893578, cbf-beta, Cbfb, CBFB, cbfbeta, PEA2, pea2-beta, Pebp2, pebp2-beta, PEBP2B, pebp2b, PEBP2b, Pebpb2, unp1266Protein level used designations for CBFB
- CBF-beta
- PEA2-beta
- PEBP2-beta
- SL3-3 enhancer factor 1 beta subunit
- SL3-3 enhancer factor 1 subunit beta
- SL3/AKV core-binding factor beta subunit
- core-binding factor subunit beta
- polyomavirus enhancer binding protein 2, beta subunit
- polyomavirus enhancer-binding protein 2 beta subunit
- core binding factor beta subunit
- core-binding factor, beta subunit
- core binding factor beta
- core-binding factor beta
- CCAAT-binding transcription factor subunit B
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