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CBR1 Produits

(Carbonyl Reductase 1 (CBR1))

Catégories

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. [provided by RefSeq, Jul 2008].

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Catégories CBR1 en vedette

CBR1 Anticorps

High quality antibodies with extensive validation data.

CBR1 Kits ELISA

Reliable ELISA kits for a wide range of species.

CBR1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CBR1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (8)
N° du produit ABIN184784
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (4)
N° du produit ABIN7444337
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7236216
Quantité 200 μL
Fiche technique Fiche technique

CBR1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975474
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1125311
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1125314
Quantité 96 tests
Fiche technique Fiche technique

CBR1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1348184
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN935034
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7418506
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CBR1

Yun, Choi, Lee, Kong, Sung, Kim, Eun: "Carbonyl reductase 1 is a new target to improve the effect of radiotherapy on head and neck squamous cell carcinoma." dans: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 264, (2019) (PubMed).

Gutiérrez-Salinas, García-Ortiz, Mondragón-Terán, Hernández-Rodríguez, Ramírez-García, Núñez-Ramos: "[Assessment of the concentrations of carbonylated proteins and carbonyl reductase enzyme in mexican women with breast cancer: A pilot study]." dans: Gaceta médica de México, Vol. 152, Issue 1, pp. 13-8, (2016) (PubMed).

Atsriku, Hoffmann, Moghaddam, Kumar, Surapaneni: "In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism." dans: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 45, Issue 6, pp. 465-80, (2015) (PubMed).

Mitani, Ito, Harada, Nakano, Inui, Ashida, Yamaji: "Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells." dans: Journal of nutritional science and vitaminology, Vol. 60, Issue 2, pp. 122-8, (2014) (PubMed).

Lim, Shin, Jo, Jyothi, Nguyen, Choi, Kim, Park, Eun, Yoon, Ha, Kim: "Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration." dans: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1784-93, (2013) (PubMed).

Rashid, Lee, Tak, Lee, Choi, Lee, Kim, Youn, Kang, Ha, Kim: "Carbonyl reductase 1 protects pancreatic β-cells against oxidative stress-induced apoptosis in glucotoxicity and glucolipotoxicity." dans: Free radical biology & medicine, Vol. 49, Issue 10, pp. 1522-33, (2010) (PubMed).

Bains, Karkling, Grigliatti, Reid, Riggs: "Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 5, pp. 1107-14, (2009) (PubMed).

Lakhman, Chen, Gonzalez-Covarrubias, Schuetz, Blanco: "Functional characterization of the promoter of human carbonyl reductase 1 (CBR1). Role of XRE elements in mediating the induction of CBR1 by ligands of the aryl hydrocarbon receptor." dans: Molecular pharmacology, Vol. 72, Issue 3, pp. 734-43, (2007) (PubMed).

Gonzalez-Covarrubias, Ghosh, Lakhman, Pendyala, Blanco: "A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 35, Issue 6, pp. 973-80, (2007) (PubMed).

Colombe, Vindrios, Michelet, Bernard: "Prostaglandin metabolism in human hair follicle." dans: Experimental dermatology, Vol. 16, Issue 9, pp. 762-9, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à CBR1

carbonyl reductase 1 (cbr1), carbonyl reductase 1 (CBR1), carbonyl reductase [NADPH] 1 (LOC100222525), carbonyl reductase 1 S homeolog (cbr1.S), carbonyl reductase (Smp_033530.3), carbonyl reductase [NADPH] 1 (LOC610164), carbonyl reductase 1 (Cbr1), 9-KPR, AW261796, CBR, Cbr, CR, hCBR1, LOC100222525, MGC131152, SDR21C1

Protein level used designations for CBR1

  • carbonyl reductase [NADPH] 1
  • carbonyl reductase 1
  • 15-hydroxyprostaglandin dehydrogenase
  • 20-beta-hydroxysteroid dehydrogenase
  • NADPH-dependent carbonyl reductase 1
  • prostaglandin 9-ketoreductase
  • prostaglandin-E(2) 9-reductase
  • carbonyl reductase
  • carbonyl reductase (NADPH) 1
  • short chain dehydrogenase/reductase family 21C, member 1
  • 20-hydroxysteroid dehydrogenase
  • prostaglandin E(2) 9-keto reductase
  • NADPH:secondary-alcohol oxidoreductase
  • Carbonyl reductase [NADPH] 1 (NADPH-dependent carbonyl reductase 1)
  • Cbr 1
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