CBX1 Produits
(Chromobox Homolog 1 (CBX1))
Catégories
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
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Catégories CBX1 en vedette
CBX1 Anticorps
High quality antibodies with extensive validation data.
CBX1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CBX1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC, FACS, ICC
Validations
- (8)
N° du produit
ABIN5542477
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, IHC (p), ICC
Validations
- (5)
N° du produit
ABIN2856369
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
N° du produit
ABIN524353
Quantité
100 μg
Fiche technique
Fiche technique
CBX1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6211808
Quantité
96 tests
Fiche technique
Fiche technique
CBX1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN667490
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348203
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348201
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CBX1
: "Polycomb repressive complex 2 and H3K27me3 cooperate with H3K9 methylation to maintain heterochromatin protein 1? at chromatin." dans: Molecular and cellular biology, Vol. 34, Issue 19, pp. 3662-74, (2014) (PubMed).: "PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures." dans: Frontiers in immunology, Vol. 3, pp. 307, (2012) (PubMed).
: "HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response." dans: Nature, Vol. 453, Issue 7195, pp. 682-6, (2008) (PubMed).
: "The Heterochromatin Protein 1 family." dans: Genome biology, Vol. 7, Issue 7, pp. 228, (2007) (PubMed).
: "The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells." dans: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4028-40, (2006) (PubMed).
: "A human protein-protein interaction network: a resource for annotating the proteome. ..." dans: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).
: "Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation." dans: Molecular and cellular biology, Vol. 23, Issue 22, pp. 8363-76, (2003) (PubMed).
: "Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 7, Issue 12, pp. 1231-42, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à CBX1
chromobox 1 (CBX1), chromobox 1 (Cbx1), chromobox homolog 1a (HP1 beta homolog Drosophila) (cbx1a), chromobox 1 S homeolog (cbx1.S), chromobox homolog 1b (HP1 beta homolog Drosophila) (cbx1b), CBX, Cbx, Cbx-rs2, cbx1, E430007M08Rik, HP1-BETA, HP1B, Hp1beta, HP1Hs-beta, HP1Hsbeta, M31, MOD1, p25beta, wu:fe14b09, zgc:55739, zgc:86924Protein level used designations for CBX1
- HP1 beta homolog
- chromobox homolog 1 (HP1 beta homolog Drosophila )
- chromobox protein homolog 1
- heterochromatin protein 1 homolog beta
- heterochromatin protein 1-beta
- heterochromatin protein p25 beta
- modifier 1 protein
- HP1 beta
- chromobox homolog 1
- heterochromatin protein p25
- chromobox homolog 1 (HP1 beta homolog)
- chromobox-like protein 1
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