CCR5 Produits
(Chemokine (C-C Motif) Receptor 5 (CCR5))
Catégories
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories CCR5 en vedette
CCR5 Anticorps
High quality antibodies with extensive validation data.
CCR5 Kits ELISA
Reliable ELISA kits for a wide range of species.
CCR5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CCR5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, FACS, IHC
Validations
- (7)
N° du produit
ABIN5611203
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC (fro)
Validations
- (6)
N° du produit
ABIN6939154
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (1)
- (6)
N° du produit
ABIN3044318
Quantité
100 μg
Fiche technique
Fiche technique
CCR5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6954650
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965712
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965711
Quantité
96 tests
Fiche technique
Fiche technique
CCR5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7491564
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348499
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN6964239
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CCR5
: "Hippocampal CCR5/RANTES Elevations in a Rodent Model of Post-Traumatic Stress Disorder: Maraviroc (a CCR5 Antagonist) Increases Corticosterone Levels and Enhances Fear Memory Consolidation." dans: Biomolecules, Vol. 10, Issue 2, (2020) (PubMed).: "Methamphetamine abuse affects gene expression in brain-derived microglia of SIV-infected macaques to enhance inflammation and promote virus targets." dans: BMC immunology, Vol. 17, Issue 1, pp. 7, (2016) (PubMed).
: "CIB1 and CIB2 are HIV-1 helper factors involved in viral entry." dans: Scientific reports, Vol. 6, pp. 30927, (2016) (PubMed).
: "Structural Insights into the Inhibitory Mechanism of an Antibody against B7-H6, a Stress-Induced Cellular Ligand for the Natural Killer Cell Receptor NKp30." dans: Journal of molecular biology, Vol. 428, Issue 22, pp. 4457-4466, (2016) (PubMed).
: "Serum concentrations of chemokines (CCL-5 and CXCL-12), chemokine receptors (CCR-5 and CXCR-4), and IL-6 in patients with posttraumatic stress disorder and avoidant personality disorder." dans: Pharmacological reports : PR, Vol. 67, Issue 6, pp. 1251-8, (2015) (PubMed).
: "A Linear Epitope in the N-Terminal Domain of CCR5 and Its Interaction with Antibody." dans: PLoS ONE, Vol. 10, Issue 6, pp. e0128381, (2015) (PubMed).
: "CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia." dans: Blood, Vol. 125, Issue 13, pp. 2087-94, (2015) (PubMed).
: "The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer." dans: British journal of cancer, Vol. 112, Issue 2, pp. 319-28, (2015) (PubMed).
: "Comparison of chemokines (CCL-5 and SDF-1), chemokine receptors (CCR-5 and CXCR-4) and IL-6 levels in patients with different severities of depression." dans: Pharmacological reports : PR, Vol. 66, Issue 5, pp. 920-6, (2014) (PubMed).
: "CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines." dans: Cancer research, Vol. 74, Issue 23, pp. 7103-14, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à CCR5
C-C motif chemokine receptor 5 (gene/pseudogene) (CCR5), chemokine (C-C motif) receptor 5 (Ccr5), chemokine (C-C motif) receptor 5 (CCR5), C-C motif chemokine receptor 5 (CCR5), AM4-7, CC-CKR-5, CCCKR5, CCR-5, CCR1-L, CCR5, CD195, CKR-5, CKR5, Ckr5, CMKBR5, Cmkbr5, GPCR, IDDM22Protein level used designations for CCR5
- C-C chemokine receptor type 5
- C-C motif chemokine receptor 5 A159A
- HIV-1 fusion coreceptor
- chemokine receptor CCR5
- chemr13
- C-C CKR-5
- CC-CKR-5
- CCR-5
- MIP-1 alpha receptor
- chemokine (C-C) receptor 5
- chemokine C-C motif receptor 5
- C-C chemokine receptor 11 like
- CC chemokine receptor 5
- chemokine receptor 5
- CC chemokine receptor type 5
- C-C chemokine receptor 5
- chemokine (C-C motif) receptor 5
- C-C chemokine receptor type 5-like
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