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CD137 Produits

(Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008].

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Catégories CD137 en vedette

CD137 Anticorps

High quality antibodies with extensive validation data.

CD137 Kits ELISA

Reliable ELISA kits for a wide range of species.

CD137 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CD137 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, FACS, WB, IHC (p)
Validations
  • (2)
  • (1)
  • (1)
N° du produit ABIN740445
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, FACS, WB, IHC, IF, IHC (p), Coat, StM
Validations
  • (8)
N° du produit ABIN6939788
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, FACS, WB
Validations
  • (5)
N° du produit ABIN7193622
Quantité 100 μL
Fiche technique Fiche technique

CD137 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970994
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960300
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN924754
Quantité 96 tests
Fiche technique Fiche technique

CD137 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7273924
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7273922
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7273923
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CD137

Lu, Li, Du, Chen, Zeng, Liu, Chen, Chen: "4-1BB Signaling Promotes Alveolar Macrophages-Mediated Pro-Fibrotic Responses and Crystalline Silica-Induced Pulmonary Fibrosis in Mice." dans: Frontiers in immunology, Vol. 9, pp. 1848, (2019) (PubMed).

Masu, Atsukawa, Nakatsuka, Shimizu, Miura, Arai, Harimoto, Kondo, Kaneko, Futagami, Kawamoto, Takahashi, Iwakiri et al.: "Anti-CD137 monoclonal antibody enhances trastuzumab-induced, natural killer cell-mediated cytotoxicity against pancreatic cancer cell lines with low human epidermal growth factor-like receptor 2 ..." dans: PLoS ONE, Vol. 13, Issue 12, pp. e0200664, (2018) (PubMed).

Claycombe, Vomhof-DeKrey, Garcia, Johnson, Uthus, Roemmich et al.: "Decreased beige adipocyte number and mitochondrial respiration coincide with increased histone methyl transferase (G9a) and reduced FGF21 gene expression in Sprague-Dawley rats fed prenatal low ..." dans: The Journal of nutritional biochemistry, Vol. 31, pp. 113-21, (2016) (PubMed).

Miller, Yang, England, Yin, Baile, Rayalam: "Isoproterenol Increases Uncoupling, Glycolysis, and Markers of Beiging in Mature 3T3-L1 Adipocytes." dans: PLoS ONE, Vol. 10, Issue 9, pp. e0138344, (2016) (PubMed).

Hodge, Holmes, Jersmann, Reynolds, Hodge: "Targeting peripheral blood pro-inflammatory cytotoxic lymphocytes by inhibiting CD137 expression: novel potential treatment for COPD." dans: BMC pulmonary medicine, Vol. 14, pp. 85, (2015) (PubMed).

Daquinag, Tseng, Salameh, Zhang, Amaya-Manzanares, Dadbin, Florez, Xu, Tong, Kolonin: "Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development." dans: Cell death and differentiation, (2014) (PubMed).

Yi, Zhao, Wang, Dai, Hellström, Hellström, Zhang: "Human and mouse CD137 have predominantly different binding CRDs to their respective ligands." dans: PLoS ONE, Vol. 9, Issue 1, pp. e86337, (2014) (PubMed).

Bellarosa, Bressan, Bigioni, Parlani, Maggi, Binaschi: "SAHA/Vorinostat induces the expression of the CD137 receptor/ligand system and enhances apoptosis mediated by soluble CD137 receptor in a human breast cancer cell line." dans: International journal of oncology, Vol. 41, Issue 4, pp. 1486-94, (2013) (PubMed).

Martinez-Forero, Azpilikueta, Bolaños-Mateo, Nistal-Villan, Palazon, Teijeira, Perez-Chacon, Morales-Kastresana, Murillo, Jure-Kunkel, Zapata, Melero: "T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 12, pp. 6694-706, (2013) (PubMed).

Fernández Do Porto, Jurado, Pasquinelli, Alvarez, Aspera, Musella, García: "CD137 differentially regulates innate and adaptive immunity against Mycobacterium tuberculosis." dans: Immunology and cell biology, Vol. 90, Issue 4, pp. 449-56, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à CD137

tumor necrosis factor receptor superfamily member 9 (TNFRSF9), TNF receptor superfamily member 9 (TNFRSF9), tumor necrosis factor receptor superfamily, member 9a (tnfrsf9a), tumor necrosis factor receptor superfamily, member 9 (Tnfrsf9), 4-1BB, A930040I11Rik, AA408498, AI325004, CD137, Cd137, CDw137, ILA, Ly63, TNFRSF9, zgc:136557

Protein level used designations for CD137

  • tumor necrosis factor receptor superfamily, member 9
  • tumor necrosis factor receptor superfamily member 9
  • 4-1BB ligand receptor
  • CD137 antigen
  • T cell antigen ILA
  • T-cell antigen 4-1BB homolog
  • T-cell antigen ILA
  • homolog of mouse 4-1BB
  • induced by lymphocyte activation (ILA)
  • interleukin-activated receptor, homolog of mouse Ly63
  • receptor protein 4-1BB
  • T-cell antigen 4-1BB
  • secreted CD137 antigen
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