CD1c Produits
(T-cell surface glycoprotein CD1c (CD1C))
Catégories
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008].
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Catégories CD1c en vedette
CD1c Anticorps
High quality antibodies with extensive validation data.
CD1c Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CD1c recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, FACS, IHC
Validations
- (5)
N° du produit
ABIN5611307
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
FACS, IHC, IP
Validations
- (4)
- (3)
N° du produit
ABIN1981870
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
FACS
Validations
- (4)
N° du produit
ABIN6240833
Quantité
100 tests
Fiche technique
Fiche technique
CD1c recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348558
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CD1c
: "Residual endotoxin contaminations in recombinant proteins are sufficient to activate human CD1c+ dendritic cells." dans: PLoS ONE, Vol. 9, Issue 12, pp. e113840, (2014) (PubMed).: "The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation." dans: Immunity, Vol. 33, Issue 6, pp. 853-62, (2010) (PubMed).
: "Membrane trafficking of CD1c on activated T cells." dans: Journal of leukocyte biology, Vol. 70, Issue 4, pp. 567-77, (2001) (PubMed).
: "Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens." dans: The Journal of experimental medicine, Vol. 192, Issue 2, pp. 281-8, (2000) (PubMed).
: "Increased numbers of dendritic cells in the bronchiolar tissues of diffuse panbronchiolitis." dans: American journal of respiratory and critical care medicine, Vol. 162, Issue 1, pp. 148-53, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à CD1c
CD1c molecule (CD1C), BDCA1, CD1, CD1A, R7Protein level used designations for CD1c
- CD1C antigen, c polypeptide
- T-cell surface glycoprotein CD1c
- cortical thymocyte antigen CD1C
- differentiation antigen CD1-alpha-3
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