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CD276 Produits

(CD276)

Catégories

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

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Catégories CD276 en vedette

CD276 Anticorps

High quality antibodies with extensive validation data.

CD276 Kits ELISA

Reliable ELISA kits for a wide range of species.

CD276 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CD276 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, FACS, IHC, ICC
Validations
  • (6)
N° du produit ABIN5611271
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7432586
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC (p), IF
Validations
  • (5)
N° du produit ABIN656709
Quantité 400 μL
Fiche technique Fiche technique

CD276 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954503
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975125
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951401
Quantité 96 tests
Fiche technique Fiche technique

CD276 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7273951
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7273959
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7273948
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CD276

Wang, Ma, Zhan, Zhang, Cao, Zhang, Shi, Chen: "B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression." dans: Cell death & disease, Vol. 11, Issue 1, pp. 55, (2020) (PubMed).

Stern, Lown, Kobe, Abou-Elkacem, Willmann, Hackel: "Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276." dans: ACS combinatorial science, Vol. 21, Issue 3, pp. 207-222, (2020) (PubMed).

Du, Hirabayashi, Ahn, Kren, Montgomery, Wang, Tiruthani, Mirlekar, Michaud, Greene, Herrera, Xu, Sun, Chen, Ma, Ferrone, Pylayeva-Gupta, Yeh, Liu, Savoldo, Ferrone, Dotti: "Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells." dans: Cancer cell, Vol. 35, Issue 2, pp. 221-237.e8, (2019) (PubMed).

Gong, Kiyotani, Sakata, Nagano, Kumehara, Baba, Besse, Yanagitani, Friboulet, Nishio, Takeuchi, Kawamoto, Fujita, Katayama: "Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer." dans: The Journal of experimental medicine, Vol. 216, Issue 4, pp. 982-1000, (2019) (PubMed).

Zhang, Wang, Marzese, Wang, Yang, Li, Zhang, Zhang, Chen, Kelly, Hua, Hoon, Mao: "B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma." dans: Laboratory investigation; a journal of technical methods and pathology, (2019) (PubMed).

Shi, Ma, Cao, Zhan, Xu, Fu, Liu, Zhang, Wang, Wang, Lu, Lu, Chen, Zhang: "B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2." dans: Cell death & disease, Vol. 10, Issue 4, pp. 308, (2019) (PubMed).

Wilson, Bachawal, Abou-Elkacem, Jensen, Machtaler, Tian, Willmann: "Spectroscopic Photoacoustic Molecular Imaging of Breast Cancer using a B7-H3-targeted ICG Contrast Agent." dans: Theranostics, Vol. 7, Issue 6, pp. 1463-1476, (2018) (PubMed).

Hock, MacPherson, McKenzie: "Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells." dans: PLoS ONE, Vol. 12, Issue 3, pp. e0172858, (2017) (PubMed).

Li, Guo, Song, Cai, Yang, Chen, Wang, Huang, Gao: "B7-H3 Promotes the Migration and Invasion of Human Bladder Cancer Cells via the PI3K/Akt/STAT3 Signaling Pathway." dans: Journal of Cancer, Vol. 8, Issue 5, pp. 816-824, (2017) (PubMed).

Quandt, Fiedler, Müller, Marsch, Seliger: "High constitutive B7-H3 expression on human keratinocytes supports T cell immunity." dans: Journal of dermatological science, Vol. 87, Issue 1, pp. 82-85, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à CD276

CD276 molecule (CD276), CD276 molecule S homeolog (cd276.S), CD276 molecule (cd276), CD276 antigen (Cd276), Cd276 molecule (Cd276), 4Ig-B7-H3, 6030411F23Rik, AU016588, B7-H3, B7h3, B7H3, B7RP-2, sc:d0645, zgc:158279

Protein level used designations for CD276

  • CD276 molecule
  • CD276 antigen-like
  • CD276 antigen homolog
  • CD276 antigen
  • B7 homolog 3
  • B7-H3
  • costimulatory molecule
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