CD33 Produits
(CD33)
Catégories
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
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Catégories CD33 en vedette
CD33 Anticorps
High quality antibodies with extensive validation data.
CD33 Kits ELISA
Reliable ELISA kits for a wide range of species.
CD33 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CD33 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), ICC, IHC (p)
Validations
- (5)
- (6)
N° du produit
ABIN687607
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
FACS, ELISA, IHC
Validations
- (2)
- (7)
N° du produit
ABIN1724812
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7440323
Quantité
100 μL
Fiche technique
Fiche technique
CD33 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965566
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965565
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962469
Quantité
96 tests
Fiche technique
Fiche technique
CD33 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7274159
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275588
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7274160
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CD33
: "Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma patients." dans: Lung cancer (Amsterdam, Netherlands), Vol. 121, pp. 70-75, (2019) (PubMed).: "Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression." dans: Scientific reports, Vol. 7, Issue 1, pp. 270, (2017) (PubMed).
: "In Vitro and In Vivo Efficacy of a Novel CD33-Targeted Thorium-227 Conjugate for the Treatment of Acute Myeloid Leukemia." dans: Molecular cancer therapeutics, Vol. 15, Issue 10, pp. 2422-2431, (2016) (PubMed).
: "Mono- and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity in vitro and in vivo against chronic lymphocytic leukemia." dans: Oncoimmunology, Vol. 5, Issue 9, pp. e1211220, (2016) (PubMed).
: "miR-17-92 plays an oncogenic role and conveys chemo-resistance to cisplatin in human prostate cancer cells." dans: International journal of oncology, Vol. 48, Issue 4, pp. 1737-48, (2016) (PubMed).
: "LukS-PV, a component of Panton-Valentine leukocidin, exerts potent activity against acute myeloid leukemia in vitro and in vivo." dans: The international journal of biochemistry & cell biology, Vol. 61C, pp. 20-28, (2015) (PubMed).
: "Vascular endothelial growth factor c/vascular endothelial growth factor receptor 3 signaling regulates chemokine gradients and lymphocyte migration from tissues to lymphatics." dans: Transplantation, Vol. 99, Issue 4, pp. 668-77, (2015) (PubMed).
: "Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells." dans: Cell death & disease, Vol. 5, pp. e1270, (2015) (PubMed).
: "Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33." dans: The Journal of biological chemistry, Vol. 289, Issue 36, pp. 25341-50, (2014) (PubMed).
: "Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo." dans: Journal of hematology & oncology, Vol. 6, Issue 1, pp. 7, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à CD33
CD33 molecule (CD33), CD33 antigen (Cd33), CD33 molecule (Cd33), gp67, p67, SIGLEC-3, Siglec-3, SIGLEC3Protein level used designations for CD33
- CD33 antigen (gp67)
- gp67
- myeloid cell surface antigen CD33
- sialic acid binding Ig-like lectin 3
- sialic acid-binding Ig-like lectin 3
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