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CD53 Produits

(CD53)

Catégories

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].

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Catégories CD53 en vedette

CD53 Anticorps

High quality antibodies with extensive validation data.

CD53 Kits ELISA

Reliable ELISA kits for a wide range of species.

CD53 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CD53 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application FACS, WB, IHC, ELISA
Validations
  • (7)
N° du produit ABIN7193233
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application FACS, IHC, ELISA
Validations
  • (5)
N° du produit ABIN7193232
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application FACS
Validations
  • (5)
  • (3)
N° du produit ABIN192139
Quantité 100 tests
Fiche technique Fiche technique

CD53 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730119
Quantité 96 tests
Fiche technique Fiche technique

CD53 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1329990
Quantité 2 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1348669
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7320175
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CD53

Zuidscherwoude, Göttfert, Dunlock, Figdor, van den Bogaart, van Spriel: "The tetraspanin web revisited by super-resolution microscopy." dans: Scientific reports, Vol. 5, pp. 12201, (2015) (PubMed).

Schatzlmaier, Supper, Göschl, Zwirzitz, Eckerstorfer, Ellmeier, Huppa, Stockinger: "Rapid multiplex analysis of lipid raft components with single-cell resolution." dans: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).

Kim, Yoon, Kim, Yook, Kim, Kim, Lee, Paik: "LPS-induced CD53 expression: a protection mechanism against oxidative and radiation stress." dans: Molecules and cells, Vol. 17, Issue 1, pp. 125-31, (2004) (PubMed).

Yunta, Rodríguez-Barbero, Arévalo, López-Novoa, Lazo: "Induction of DNA synthesis by ligation of the CD53 tetraspanin antigen in primary cultures of mesangial cells." dans: Kidney international, Vol. 63, Issue 2, pp. 534-42, (2003) (PubMed).

Puls, Hogquist, Reilly, Wright: "CD53, a thymocyte selection marker whose induction requires a lower affinity TCR-MHC interaction than CD69, but is up-regulated with slower kinetics." dans: International immunology, Vol. 14, Issue 3, pp. 249-58, (2002) (PubMed).

Szöllósi, Horejsí, Bene, Angelisová, Damjanovich: "Supramolecular complexes of MHC class I, MHC class II, CD20, and tetraspan molecules (CD53, CD81, and CD82) at the surface of a B cell line JY." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 7, pp. 2939-46, (1996) (PubMed).

Crook, Hunt: "Enrichment of early fetal-liver hemopoietic stem cells of the rat using monoclonal antibodies against the transferrin receptor, Thy-1, and MRC-OX82." dans: Developmental immunology, Vol. 4, Issue 4, pp. 235-46, (1996) (PubMed).

Carmo, Wright: "Association of the transmembrane 4 superfamily molecule CD53 with a tyrosine phosphatase activity." dans: European journal of immunology, Vol. 25, Issue 7, pp. 2090-5, (1995) (PubMed).

Tomlinson, Hanke, Hughes, Barclay, Scholl, Hünig, Wright: "Characterization of mouse CD53: epitope mapping, cellular distribution and induction by T cell receptor engagement during repertoire selection." dans: European journal of immunology, Vol. 25, Issue 8, pp. 2201-5, (1995) (PubMed).

Olweus, Lund-Johansen, Terstappen: "CD64/Fc gamma RI is a granulo-monocytic lineage marker on CD34+ hematopoietic progenitor cells." dans: Blood, Vol. 85, Issue 9, pp. 2402-13, (1995) (PubMed).

Synonymes et noms alternatifs relatifs à CD53

CD53 antigen (Cd53), CD53 molecule (CD53), Cd53 molecule (Cd53), AI323659, MOX44, Ox-44, OX44, Tspan25, TSPAN25

Protein level used designations for CD53

  • cell surface glycoprotein CD53
  • leukocyte surface antigen CD53
  • CD53 antigen
  • CD53 glycoprotein
  • CD53 tetraspan antigen
  • antigen MOX44 identified by monoclonal antibody MRC-OX44
  • cell surface antigen
  • tetraspanin-25
  • transmembrane glycoprotein
  • tspan-25
  • leukocyte antigen MRC OX-44
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