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CD6 Produits

(CD6)

Catégories

This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].

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Catégories CD6 en vedette

CD6 Anticorps

High quality antibodies with extensive validation data.

CD6 Kits ELISA

Reliable ELISA kits for a wide range of species.

CD6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CD6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS, IHC, ELISA, ICC
Validations
  • (7)
N° du produit ABIN5542301
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC, ELISA
Validations
  • (6)
N° du produit ABIN5542300
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
  • (4)
N° du produit ABIN1098118
Quantité 100 μL
Fiche technique Fiche technique

CD6 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1889385
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1889429
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN2708164
Quantité 96 tests
Fiche technique Fiche technique

CD6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274212
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Human Cells
Validations
  • (1)
N° du produit ABIN7320847
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7317120
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CD6

Enyindah-Asonye, Li, Ruth, Spassov, Hebron, Zijlstra, Moasser, Wang, Singer, Cui, Ohara, Rasmussen, Fox, Lin: "CD318 is a ligand for CD6." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 33, pp. E6912-E6921, (2017) (PubMed).

Alonso, Buors, Le Dantec, Hillion, Pers, Saraux, Montero, Marianowski, Loisel, Devauchelle, Youinou, Renaudineau: "Aberrant expression of CD6 on B-cell subsets from patients with Sjögren's syndrome." dans: Journal of autoimmunity, Vol. 35, Issue 4, pp. 336-41, (2010) (PubMed).

Nair, Melarkode, Rajkumar, Montero: "CD6 synergistic co-stimulation promoting proinflammatory response is modulated without interfering with the activated leucocyte cell adhesion molecule interaction." dans: Clinical and experimental immunology, Vol. 162, Issue 1, pp. 116-30, (2010) (PubMed).

Piriou-Guzylack, Salmon: "Membrane markers of the immune cells in swine: an update." dans: Veterinary research, Vol. 39, Issue 6, pp. 54, (2008) (PubMed).

Castro, Oliveira, Nunes, Fabre, Barbosa, Peixoto, Brown, Parnes, Bismuth, Moreira, Rocha, Carmo: "Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 7, pp. 4351-61, (2007) (PubMed).

Sarrias, Farnós, Mota, Sánchez-Barbero, Ibáñez, Gimferrer, Vera, Fenutría, Casals, Yélamos, Lozano: "CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 28, pp. 11724-9, (2007) (PubMed).

Hassan, Simmonds, Clarkson, Hanrahan, Puklavec, Bomb, Barclay, Brown: "CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76." dans: Molecular and cellular biology, Vol. 26, Issue 17, pp. 6727-38, (2006) (PubMed).

Zimmerman, Joosten, Torensma, Parnes, van Leeuwen, Figdor: "Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells." dans: Blood, Vol. 107, Issue 8, pp. 3212-20, (2006) (PubMed).

Castro, Nunes, Oliveira, Tavares, Simões, Parnes, Moreira, Carmo: "OX52 is the rat homologue of CD6: evidence for an effector function in the regulation of CD5 phosphorylation." dans: Journal of leukocyte biology, Vol. 73, Issue 1, pp. 183-90, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à CD6

CD6 antigen (Cd6), CD6 molecule (CD6), Cd6 molecule (Cd6), OX52, TP120

Protein level used designations for CD6

  • T-cell differentiation antigen CD6
  • CD6 antigen
  • T12
  • CD6 antigen, Tp120
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