CD97 Produits
(CD97)
Catégories
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011].
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Catégories CD97 en vedette
CD97 Anticorps
High quality antibodies with extensive validation data.
CD97 Kits ELISA
Reliable ELISA kits for a wide range of species.
CD97 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CD97 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
IHC, ELISA, FACS
Validations
- (6)
N° du produit
ABIN7193255
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (4)
N° du produit
ABIN741495
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
N° du produit
ABIN560261
Quantité
100 μg
Fiche technique
Fiche technique
CD97 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965617
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965616
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6720027
Quantité
1 kit
Fiche technique
Fiche technique
CD97 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348745
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348744
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
N° du produit
ABIN1330008
Quantité
2 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CD97
: "Role of CD97 small isoform in human cervical carcinoma." dans: International journal of experimental pathology, Vol. 100, Issue 1, pp. 19-24, (2019) (PubMed).: "Emerging Bordetella pertussis Strains Induce Enhanced Signaling of Human Pattern Recognition Receptors TLR2, NOD2 and Secretion of IL-10 by Dendritic Cells." dans: PLoS ONE, Vol. 12, Issue 1, pp. e0170027, (2017) (PubMed).
: "Skeletal muscle expression of the adhesion-GPCR CD97: CD97 deletion induces an abnormal structure of the sarcoplasmatic reticulum but does not impair skeletal muscle function." dans: PLoS ONE, Vol. 9, Issue 6, pp. e100513, (2014) (PubMed).
: "Shear stress-dependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD55." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 7, pp. 3740-8, (2013) (PubMed).
: "The invasion and metastasis promotion role of CD97 small isoform in gastric carcinoma." dans: PLoS ONE, Vol. 7, Issue 6, pp. e39989, (2012) (PubMed).
: "Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctions." dans: PLoS ONE, Vol. 5, Issue 1, pp. e8507, (2010) (PubMed).
: "Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 9, pp. 6574-83, (2008) (PubMed).
: "Improved antibacterial host defense and altered peripheral granulocyte homeostasis in mice lacking the adhesion class G protein receptor CD97." dans: Infection and immunity, Vol. 75, Issue 3, pp. 1144-53, (2007) (PubMed).
: "Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55." dans: The Journal of biological chemistry, Vol. 282, Issue 30, pp. 22023-32, (2007) (PubMed).
: "Individual cell-based models of tumor-environment interactions: Multiple effects of CD97 on tumor invasion." dans: The American journal of pathology, Vol. 169, Issue 5, pp. 1802-11, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à CD97
adhesion G protein-coupled receptor E5 (Adgre5), adhesion G protein-coupled receptor E5 (ADGRE5), AA409984, TM7LN1Protein level used designations for CD97
- EGF-TM7 receptor
- CD97 antigen
- leukocyte antigen CD97
- seven transmembrane helix receptor
- seven-span transmembrane protein
- seven-transmembrane, heterodimeric receptor associated with inflammation
- CD97 large isoform
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