CDC25B Produits
(Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
Catégories
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008].
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Catégories CDC25B en vedette
CDC25B Anticorps
High quality antibodies with extensive validation data.
CDC25B Kits ELISA
Reliable ELISA kits for a wide range of species.
CDC25B Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CDC25B recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
N° du produit
ABIN756967
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p)
Validations
- (4)
N° du produit
ABIN756982
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (3)
N° du produit
ABIN391380
Quantité
400 μL
Fiche technique
Fiche technique
CDC25B recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380386
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380112
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4882277
Quantité
96 tests
Fiche technique
Fiche technique
CDC25B recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348794
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348796
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7401014
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CDC25B
: "The BET bromodomain inhibitor JQ1 radiosensitizes non-small cell lung cancer cells by upregulating p21." dans: Cancer letters, Vol. 391, pp. 141-151, (2017) (PubMed).: "Conformational flexibility of the complete catalytic domain of Cdc25B phosphatases." dans: Proteins, Vol. 84, Issue 11, pp. 1567-1575, (2016) (PubMed).
: "IFI27, a novel epidermal growth factor-stabilized protein, is functionally involved in proliferation and cell cycling of human epidermal keratinocytes." dans: Cell proliferation, (2015) (PubMed).
: "Lats1 suppresses centrosome overduplication by modulating the stability of Cdc25B." dans: Scientific reports, Vol. 5, pp. 16173, (2015) (PubMed).
: "Ser149 is another potential PKA phosphorylation target of Cdc25B in G2/M transition of fertilized mouse eggs." dans: The Journal of biological chemistry, Vol. 286, Issue 12, pp. 10356-66, (2011) (PubMed).
: "Cdc25A and cdc25B expression in malignant lymphoma of the thyroid: correlation with histological subtypes and cell proliferation." dans: International journal of molecular medicine, Vol. 13, Issue 3, pp. 431-5, (2004) (PubMed).
: "Nuclear export signal in CDC25B." dans: Biochemical and biophysical research communications, Vol. 316, Issue 1, pp. 226-32, (2004) (PubMed).
: "Coordinate expression of Cdc25B and ER-alpha is frequent in low-grade endometrioid endometrial carcinoma but uncommon in high-grade endometrioid and nonendometrioid carcinomas." dans: Cancer research, Vol. 63, Issue 19, pp. 6195-9, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à CDC25B
cell division cycle 25B (cdc25b), cell division cycle 25B (CDC25B), cell division cycle 25B (Cdc25b), AI604853, CDC25BProtein level used designations for CDC25B
- cell division cycle 25 homolog B
- cell division cycle 25 homolog B (S. pombe)
- M-phase inducer phosphatase 2-like
- m-phase inducer phosphatase 2-like
- cell division cycle 25B
- M-phase inducer phosphatase 2
- dual specificity phosphatase Cdc25B
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