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CDC42BPA Produits

(CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))

Catégories

The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008].

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Catégories CDC42BPA en vedette

CDC42BPA Anticorps

High quality antibodies with extensive validation data.

CDC42BPA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CDC42BPA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (3)
N° du produit ABIN2855436
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
N° du produit ABIN7248404
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN563644
Quantité 100 μg
Fiche technique Fiche technique

CDC42BPA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1348835
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN5509022
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CDC42BPA

Cmejla, Ptackova, Petrak, Savvulidi, Cerny, Sebesta, Vyoral: "Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake." dans: Biochemical and biophysical research communications, Vol. 395, Issue 2, pp. 163-7, (2010) (PubMed).

Dong, Leung, Manser, Lim: "Cdc42 antagonizes inductive action of cAMP on cell shape, via effects of the myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) on myosin light chain phosphorylation." dans: European journal of cell biology, Vol. 81, Issue 4, pp. 231-42, (2002) (PubMed).

Tan, Seow, Lim, Leung: "Intermolecular and intramolecular interactions regulate catalytic activity of myotonic dystrophy kinase-related Cdc42-binding kinase alpha." dans: Molecular and cellular biology, Vol. 21, Issue 8, pp. 2767-78, (2001) (PubMed).

Lam, Pham, Nguyen, Morris: "Characterization of a monoclonal antibody panel shows that the myotonic dystrophy protein kinase, DMPK, is expressed almost exclusively in muscle and heart." dans: Human molecular genetics, Vol. 9, Issue 14, pp. 2167-73, (2000) (PubMed).

Zhao, Loyer, Li, Valentine, Kidd, Kraft: "Cloning and chromosomal location of a novel member of the myotonic dystrophy family of protein kinases." dans: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10013-20, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à CDC42BPA

CDC42 binding protein kinase alpha (CDC42BPA), CDC42 binding protein kinase alpha (Cdc42bpa), GDNF family receptor alpha 2 (GFRA2), serine/threonine-protein kinase MRCK alpha (LOC100182779), CDC42 binding protein kinase alpha (DMPK-like) (CDC42BPA), serine/threonine-protein kinase MRCK alpha (LOC100545977), A930014J19Rik, CDC42BPA, DMPK-like, MRCK, Mrck, MRCKA, PK428, Pk428

Protein level used designations for CDC42BPA

  • CDC42 binidng protein kinase beta
  • CDC42-binding protein kinase alpha (DMPK-like)
  • DMPK-like alpha
  • MRCK alpha
  • myotonic dystrophy kinase-related CDC42-binding kinase alpha
  • myotonic dystrophy kinase-related CDC42-binding protein kinase alpha
  • myotonic dystrophy protein kinase-like alpha
  • ser-thr protein kinase PK428
  • ser-thr protein kinase related to the myotonic dystrophy protein kinase
  • serine/threonine-protein kinase MRCK alpha
  • CDC42-binding protein kinase alpha
  • Ser-Thr protein kinase related to the myotonic dystrophy protein kinase
  • mytonic dystrophy kinase-related Cdc42-binding kinase
  • myotonic dystrophy kinase-related CDC-42-binding kinase-alpha
  • CDC42 binding protein kinase alpha (DMPK-like)
  • CDC42 binding protein kinase alpha-like
  • serine/threonine-protein kinase MRCK alpha-like
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