CDC6 Produits
(Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
Catégories
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008].
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Catégories CDC6 en vedette
CDC6 Anticorps
High quality antibodies with extensive validation data.
CDC6 Kits ELISA
Reliable ELISA kits for a wide range of species.
CDC6 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CDC6 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, PLA
Validations
- (5)
N° du produit
ABIN514244
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, IP
Validations
- (7)
N° du produit
ABIN2451939
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7147287
Quantité
100 μg
Fiche technique
Fiche technique
CDC6 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380160
Quantité
2 x 96 tests
Fiche technique
Fiche technique
CDC6 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348865
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348864
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3091476
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits CDC6
: "FOXM1 and androgen receptor co-regulate CDC6 gene transcription and DNA replication in prostate cancer cells." dans: Biochimica et biophysica acta, Vol. 1839, Issue 4, pp. 297-305, (2014) (PubMed).: "A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication." dans: Science signaling, Vol. 6, Issue 262, pp. ra10, (2013) (PubMed).
: "Cdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A." dans: Molecular and cellular biology, Vol. 24, Issue 4, pp. 1614-27, (2004) (PubMed).
: "Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1." dans: The EMBO journal, Vol. 22, Issue 3, pp. 704-12, (2003) (PubMed).
: "Caspase-3-mediated cleavage of Cdc6 induces nuclear localization of p49-truncated Cdc6 and apoptosis." dans: Molecular biology of the cell, Vol. 14, Issue 10, pp. 4250-9, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à CDC6
cell division cycle 6 (CDC6), cell division cycle 6 (Cdc6), CDC18L, HsCDC6, HsCDC18Protein level used designations for CDC6
- CDC6 cell division cycle 6 homolog
- CDC6-related protein
- cdc18-related protein
- cell division control protein 6 homolog
- cell division cycle 6 homolog
- p62(cdc6)
- CDC18(S.pombe)
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