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CDCP1 Produits

(CUB Domain Containing Protein 1 (CDCP1))

Catégories

The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Catégories CDCP1 en vedette

CDCP1 Anticorps

High quality antibodies with extensive validation data.

CDCP1 Kits ELISA

Reliable ELISA kits for a wide range of species.

CDCP1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CDCP1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7434047
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (4)
N° du produit ABIN3187811
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
N° du produit ABIN7073600
Quantité 100 μL
Fiche technique Fiche technique

CDCP1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955136
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1568906
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730346
Quantité 96 tests
Fiche technique Fiche technique

CDCP1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274293
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274295
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274291
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CDCP1

Sandercock, Rust, Guillard, Sachsenmeier, Holoweckyj, Hay, Flynn, Huang, Yan, Herpers, Price, Soden, Freeth, Jermutus, Hollingsworth, Minter: "Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling." dans: Molecular cancer, Vol. 14, pp. 147, (2015) (PubMed).

Iwata, Torok-Storb, Wayner, Carter: "CDCP1 identifies a CD146 negative subset of marrow fibroblasts involved with cytokine production." dans: PLoS ONE, Vol. 9, Issue 10, pp. e109304, (2014) (PubMed).

Sasaroli, Gimotty, Pathak, Hammond, Kougioumtzidou, Katsaros, Buckanovich, Devarajan, Sandaltzopoulos, Godwin, Scholler, Coukos: "Novel surface targets and serum biomarkers from the ovarian cancer vasculature." dans: Cancer biology & therapy, Vol. 12, Issue 3, pp. 169-80, (2011) (PubMed).

Kelly, Chan, Martinson, Kadoya, Ostertag, Ross, Richardson, Carpenter, DAmour, Kroon, Moorman, Baetge, Bang: "Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells." dans: Nature biotechnology, Vol. 29, Issue 8, pp. 750-6, (2011) (PubMed).

He, Wortmann, Burke, Reid, Adams, Abdul-Jabbar, Quigley, Leduc, Kirchhofer, Hooper et al.: "Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain ..." dans: The Journal of biological chemistry, Vol. 285, Issue 34, pp. 26162-73, (2010) (PubMed).

Hooper, Zijlstra, Aimes, Liang, Claassen, Tarin, Testa, Quigley: "Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen." dans: Oncogene, Vol. 22, Issue 12, pp. 1783-94, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à CDCP1

CUB domain containing protein 1 (CDCP1), CUB domain containing protein 1 (Cdcp1), CUB domain containing protein 1a (cdcp1a), 9030022E12Rik, AA409659, CD318, E030027H19Rik, RGD1305578, SIMA135, TRASK, zgc:113071

Protein level used designations for CDCP1

  • CUB domain-containing protein 1
  • membrane glycoprotein gp140
  • subtractive immunization M plus HEp3-associated 135 kDa protein
  • transmembrane and associated with src kinases
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