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CDKN1C Produits

(Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].

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Catégories CDKN1C en vedette

CDKN1C Anticorps

High quality antibodies with extensive validation data.

CDKN1C Kits ELISA

Reliable ELISA kits for a wide range of species.

CDKN1C Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CDKN1C recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, FACS, IHC
Validations
  • (6)
N° du produit ABIN7193625
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, FACS, IHC, ICC
Validations
  • (8)
N° du produit ABIN7193626
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application IHC (f)
Validations
  • (3)
N° du produit ABIN7504181
Quantité 100 μg
Fiche technique Fiche technique

CDKN1C recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380426
Quantité 2 x 96 tests
Fiche technique Fiche technique

CDKN1C recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122539
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1349015
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3134280
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CDKN1C

Zhang, Li, Dong, Wu: "Long non-coding RNA NEAT1 regulates E2F3 expression by competitively binding to miR-377 in non-small cell lung cancer." dans: Oncology letters, Vol. 14, Issue 4, pp. 4983-4988, (2018) (PubMed).

Mochizuki, Tamai, Imai, Sugawara, Ogama, Nakamura, Matsuura, Yamaguchi, Satoh, Sato, Motohashi, Sugamura, Tanaka: "CD271 regulates the proliferation and motility of hypopharyngeal cancer cells." dans: Scientific reports, Vol. 6, pp. 30707, (2016) (PubMed).

Ma, Chen, Wright, Pillai, Chellappan, Cress: "CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner." dans: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9813-22, (2010) (PubMed).

Graña, Reddy: "Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)." dans: Oncogene, Vol. 11, Issue 2, pp. 211-9, (1995) (PubMed).

Lee, Reynisdóttir, Massagué: "Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution." dans: Genes & development, Vol. 9, Issue 6, pp. 639-49, (1995) (PubMed).

Matsuoka, Edwards, Bai, Parker, Zhang, Baldini, Harper, Elledge: "p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene." dans: Genes & development, Vol. 9, Issue 6, pp. 650-62, (1995) (PubMed).

Synonymes et noms alternatifs relatifs à CDKN1C

cyclin dependent kinase inhibitor 1C (CDKN1C), cyclin-dependent kinase inhibitor 1Ca (cdkn1ca), cyclin-dependent kinase inhibitor 1C (P57) (Cdkn1c), cyclin-dependent kinase inhibitor 1C (Cdkn1c), AL024410, BWCR, BWS, cb961, CDKI, KIP2, Kip2, p27Xic1-a, p57, p57(kip2), p57Kip2, p57KIP2, WBS, zgc:86618

Protein level used designations for CDKN1C

  • cyclin-dependent kinase inhibitor 1C
  • cyclin-dependent kinase inhibitor p57
  • cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • p57kip2
  • cyclin-dependent kinase inhibitor 1C, p57
  • p57KIP2 A3sh
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