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CDKN3 Produits

(Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Catégories

The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

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Catégories CDKN3 en vedette

CDKN3 Anticorps

High quality antibodies with extensive validation data.

CDKN3 Kits ELISA

Reliable ELISA kits for a wide range of species.

CDKN3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CDKN3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6260728
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
N° du produit ABIN3022822
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7148919
Quantité 100 μg
Fiche technique Fiche technique

CDKN3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966182
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955168
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5648167
Quantité 96 tests
Fiche technique Fiche technique

CDKN3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122543
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1349027
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1349026
Quantité 25 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CDKN3

Jiang, Xia, Li, Deng, Zhao, Shi, Wang, Sun: "High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer." dans: International journal of cancer. Journal international du cancer, Vol. 126, Issue 5, pp. 1263-74, (2010) (PubMed).

Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." dans: Human genetics, Vol. 128, Issue 4, pp. 433-41, (2010) (PubMed).

Okamoto, Kitabayashi, Taya: "KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction." dans: Biochemical and biophysical research communications, Vol. 351, Issue 1, pp. 216-22, (2006) (PubMed).

Hsieh, Yao, Lai, Yang: "Transcriptional repression activity of PAX3 is modulated by competition between corepressor KAP1 and heterochromatin protein 1." dans: Biochemical and biophysical research communications, Vol. 349, Issue 2, pp. 573-81, (2006) (PubMed).

Chinami, Yano, Yang, Salahuddin, Moriyama, Shiroishi, Turner, Shirakawa, Adra et al.: "Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP..." dans: The Journal of biological chemistry, Vol. 280, Issue 17, pp. 17235-42, (2005) (PubMed).

Yeh, Lu, Chao, Chao: "Abolishment of the interaction between cyclin-dependent kinase 2 and Cdk-associated protein phosphatase by a truncated KAP mutant." dans: Biochemical and biophysical research communications, Vol. 305, Issue 2, pp. 311-4, (2003) (PubMed).

Lee, Reimer, Fang, Iruela-Arispe, Aaronson: "Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression." dans: Molecular and cellular biology, Vol. 20, Issue 5, pp. 1723-32, (2000) (PubMed).

Yeh, Lu, Chen, Peng, Liaw: "Aberrant transcripts of the cyclin-dependent kinase-associated protein phosphatase in hepatocellular carcinoma." dans: Cancer research, Vol. 60, Issue 17, pp. 4697-700, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à CDKN3

cyclin dependent kinase inhibitor 3 (CDKN3), cyclin-dependent kinase inhibitor 3 (CDKN3), cyclin-dependent kinase inhibitor 3 (cdkn3), cyclin-dependent kinase inhibitor 3 (Cdkn3), cyclin dependent kinase inhibitor 3 (Cdkn3), inhibitor/interactor with cyclin-dependent kinase (ICK6), 2410006H10Rik, CDI1, CDKN3, CIP2, inhibitor/interactor with cyclin-dependent kinase, K24G6.15, K24G6_15, KAP, KAP1, KIP-RELATED PROTEIN 3, KRP3

Protein level used designations for CDKN3

  • CDK2-associated dual specificity phosphatase
  • CDK2-associated dual-specificity phosphatase
  • Cdk-associated protein phosphatase
  • cyclin-dependent kinase interacting protein 2
  • cyclin-dependent kinase interactor 1
  • cyclin-dependent kinase-interacting protein 2
  • kinase associated phosphatase
  • kinase-associated phosphatase
  • cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase)
  • cyclin-dependent kinase inhibitor 3
  • Kinase-associated phosphatase
  • Inhibitor/interactor of CDK protein 6
  • KIP-related protein 3
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