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CELF1 Produits

(CUGBP, Elav-Like Family Member 1 (CELF1))

Catégories

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Catégories CELF1 en vedette

CELF1 Anticorps

High quality antibodies with extensive validation data.

CELF1 Kits ELISA

Reliable ELISA kits for a wide range of species.

CELF1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CELF1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP
Validations
  • (5)
N° du produit ABIN6138399
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN948978
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN657957
Quantité 400 μL
Fiche technique Fiche technique

CELF1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Sheep
Analytical Method
Validations
N° du produit ABIN1773938
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1743034
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1744255
Quantité 96 tests
Fiche technique Fiche technique

CELF1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1350750
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3091407
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3133586
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CELF1

Liu, Ouyang, Rao, Zou, Xiao, Chung, Wu, Donahue, Gorospe, Wang: "Competition between RNA-binding proteins CELF1 and HuR modulates MYC translation and intestinal epithelium renewal." dans: Molecular biology of the cell, Vol. 26, Issue 10, pp. 1797-810, (2015) (PubMed).

Chung, Rao, Zou, Liu, Xiao, Gu, Turner, Yang, Wang: "Jnk2 deletion disrupts intestinal mucosal homeostasis and maturation by differentially modulating RNA-binding proteins HuR and CUGBP1." dans: American journal of physiology. Cell physiology, Vol. 306, Issue 12, pp. C1167-75, (2014) (PubMed).

Yu, Rao, Zou, Liu, Xiao, Ouyang, Cao, Gorospe, Wang: "Competitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function." dans: Molecular biology of the cell, Vol. 24, Issue 2, pp. 85-99, (2013) (PubMed).

de Haro, Al-Ramahi, Jones, Holth, Timchenko, Botas: "Smaug/SAMD4A restores translational activity of CUGBP1 and suppresses CUG-induced myopathy." dans: PLoS genetics, Vol. 9, Issue 4, pp. e1003445, (2013) (PubMed).

Xiao, Ford, Xu, Yan, Lee, Gonzales, West, Holtzman, Lee: "Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 39, pp. 13587-96, (2012) (PubMed).

Xiao, Cui, Rao, Zou, Liu, Smith, Turner, Gorospe, Wang: "Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyamines." dans: Molecular biology of the cell, Vol. 22, Issue 17, pp. 3055-69, (2011) (PubMed).

Ward, Rimer, Killian, Dowling, Cooper: "CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1." dans: Human molecular genetics, Vol. 19, Issue 18, pp. 3614-22, (2010) (PubMed).

Hashem, Galloway, Mori, Willemsen, Oostra, Paylor, Nelson: "Ectopic expression of CGG containing mRNA is neurotoxic in mammals." dans: Human molecular genetics, Vol. 18, Issue 13, pp. 2443-51, (2009) (PubMed).

Orengo, Chambon, Metzger, Mosier, Snipes, Cooper: "Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 7, pp. 2646-51, (2008) (PubMed).

Kress, Gautier-Courteille, Osborne, Babinet, Paillard: "Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice." dans: Molecular and cellular biology, Vol. 27, Issue 3, pp. 1146-57, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à CELF1

CUGBP Elav-like family member 1 (CELF1), CUGBP, Elav-like family member 1 (Celf1), cugbp, Elav-like family member 1 (celf1), CUGBP, Elav-like family member 1 (CELF1), CUGBP Elav-like family member 1 L homeolog (celf1.L), CUGBP Elav-like family member 1 (Celf1), 1600010O03Rik, AA407467, brul, Bruno-like, BRUNOL2, Brunol2, brunol2, cb920, CUG-BP, cug-bp, CUG-BP1, cug-bp1, CUGBP, cugbp, CUGBP1, Cugbp1, cugbp1, cugbp1-a, D2Wsu101e, EDEN-BP, eden-bp, edenbp, hNab50, HNAB50, NAB50, nab50, NAPOR

Protein level used designations for CELF1

  • CUG triplet repeat, RNA binding protein 1
  • CUGBP Elav-like family member 1
  • 50 kDa nuclear polyadenylated RNA-binding protein
  • CELF-1
  • CUG RNA-binding protein
  • CUG triplet repeat RNA-binding protein 1
  • CUG triplet repeat, RNA-binding protein 1
  • CUG-BP- and ETR-3-like factor 1
  • CUG-BP1
  • EDEN-BP homolog
  • RNA-binding protein BRUNOL-2
  • bruno-like 2
  • bruno-like protein 2
  • deadenylation factor CUG-BP
  • embryo deadenylation element binding protein
  • embryo deadenylation element-binding protein homolog
  • nuclear polyadenylated RNA-binding protein, 50-kD
  • brain protein F41
  • deadenylation factor EDEN-BP
  • EDEN-BP/Bruno-like protein
  • CELF-1A
  • CUG triplet repeat RNA-binding protein 1-A
  • CUG-BP- and ETR-3-like factor 1-A
  • CUG-BP1-A
  • CUGBP Elav-like family member 1-A
  • EDEN-BP-A
  • RNA-binding protein BRUNOL-2-A
  • bruno-like protein 2-A
  • embryo deadenylation element-binding protein A
  • p53/p55
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