CFTR Produits
(Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
Catégories
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008].
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Catégories CFTR en vedette
CFTR Anticorps
High quality antibodies with extensive validation data.
CFTR Kits ELISA
Reliable ELISA kits for a wide range of species.
CFTR Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CFTR recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
IHC, WB, IP, ICC
Validations
- (3)
N° du produit
ABIN7434899
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC (f), FACS
Validations
- (3)
N° du produit
ABIN6939092
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
IF, WB
Validations
- (3)
N° du produit
ABIN6138469
Quantité
100 μL
Fiche technique
Fiche technique
CFTR recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966205
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962401
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955205
Quantité
96 tests
Fiche technique
Fiche technique
CFTR recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1349232
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7396334
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3112877
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits CFTR
: "β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis." dans: The American journal of pathology, Vol. 189, Issue 4, pp. 813-825, (2019) (PubMed).: "Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis." dans: Nature medicine, Vol. 23, Issue 5, pp. 590-600, (2017) (PubMed).
: "High level of CFTR expression is associated with tumor aggression and knockdown of CFTR suppresses proliferation of ovarian cancer in vitro and in vivo." dans: Oncology reports, Vol. 33, Issue 5, pp. 2227-34, (2015) (PubMed).
: "Exaggerated apoptosis and NF-kappaB activation in pancreatic and tracheal cystic fibrosis cells." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 11, pp. 2939-48, (2007) (PubMed).
: "CFTR regulates phagosome acidification in macrophages and alters bactericidal activity." dans: Nature cell biology, Vol. 8, Issue 9, pp. 933-44, (2006) (PubMed).
: "Acceleration of glutathione efflux and inhibition of gamma-glutamyltranspeptidase sensitize metastatic B16 melanoma cells to endothelium-induced cytotoxicity." dans: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 6950-9, (2005) (PubMed).
: "Differential regulation of cystic fibrosis transmembrane conductance regulator by interferon gamma in mast cells and epithelial cells." dans: The Journal of pharmacology and experimental therapeutics, Vol. 315, Issue 2, pp. 563-70, (2005) (PubMed).
: "PTH stimulates a Cl(-)-dependent and EIPA-sensitive current in chick proximal tubule cells in culture." dans: American journal of physiology. Renal physiology, Vol. 284, Issue 5, pp. F987-95, (2003) (PubMed).
: "Polarization of specific tropomyosin isoforms in gastrointestinal epithelial cells and their impact on CFTR at the apical surface." dans: Molecular biology of the cell, Vol. 14, Issue 11, pp. 4365-75, (2003) (PubMed).
: "Expression and functional characterization of CFTR in mast cells." dans: Journal of leukocyte biology, Vol. 71, Issue 1, pp. 54-64, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à CFTR
cystic fibrosis transmembrane conductance regulator (CFTR), cystic fibrosis transmembrane conductance regulator (cftr-A), cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (CFTR), cystic fibrosis transmembrane conductance regulator (Cftr), cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (cftr), ABC35, abc35, ABCC7, Abcc7, abcc7, AW495489, CF, CFTR, CFTR/MRP, cftr/mrp, dJ760C5.1, MRP7, mrp7, RGD1561193, si:dkey-270i2.2, TNR-CFTR, tnr-cftr, xcftrProtein level used designations for CFTR
- cAMP-dependent chloride channel
- channel conductance-controlling ATPase
- cystic fibrosis transmembrane conductance regulator
- cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)
- ATP-binding cassette sub-family C member 7
- ATP-binding cassette transporter sub-family C member 7
- ATP-binding cassette, subfamily c, member 7
- cystic fibrosis transmembrane conductance regulator homolog
- cystic fibrosis transmembrane conductance regulator homolog; ATP-binding cassette, subfamily c, member 7
- CFTR chloride channel
- chloride channel
- CFTR cAMP-dependent chloride channel protein
- Channel conductance-controlling ATPase
- abcc7
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