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CHD4 Produits

(Chromodomain Helicase DNA Binding Protein 4 (CHD4))
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. [provided by RefSeq, Jul 2008].

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Catégories CHD4 en vedette

CHD4 Anticorps

High quality antibodies with extensive validation data.

CHD4 Kits ELISA

Reliable ELISA kits for a wide range of species.

CHD4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CHD4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (6)
N° du produit ABIN7255670
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (2)
  • (5)
N° du produit ABIN560357
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
N° du produit ABIN6138512
Quantité 100 μL
Fiche technique Fiche technique

CHD4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954775
Quantité 96 tests
Fiche technique Fiche technique

CHD4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1349294
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7397285
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7403291
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CHD4

Guel, Scholtissek, Siegl, Fetter, Mayer, Bieber, Wenzel: "Dermatomyositis autoantigen CHD4 forms immune stimulatory complexes with endogenous DNA." dans: Experimental dermatology, (2023) (PubMed).

Yen, Sharma, Cols, Lau, Chaudhry, Chowdhury, Yewdell, Vaidyanathan, Sun, Coffre, Pucella, Chen, Jasin, Sun, Rudensky, Koralov, Chaudhuri: "Distinct Requirements of CHD4 during B Cell Development and Antibody Response." dans: Cell reports, Vol. 27, Issue 5, pp. 1472-1486.e5, (2019) (PubMed).

Crosswhite, Podsiadlowska, Curtis, Gao, Xia, Srinivasan, Griffin: "CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity." dans: The Journal of clinical investigation, Vol. 126, Issue 6, pp. 2254-66, (2016) (PubMed).

Nishibuchi, Shibata, Hayakawa, Hayakawa, Ohtani, Sinmyozu, Tagami, Nakayama: "Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex." dans: The Journal of biological chemistry, Vol. 289, Issue 42, pp. 28956-70, (2014) (PubMed).

Gu, Hu, Ebrahem, Crabb, Mahfouz, Radivoyevitch, Crabb, Saunthararajah: "Runx1 regulation of Pu.1 corepressor/coactivator exchange identifies specific molecular targets for leukemia differentiation therapy." dans: The Journal of biological chemistry, Vol. 289, Issue 21, pp. 14881-95, (2014) (PubMed).

Ingram, Curtis, Silasi-Mansat, Lupu, Griffin: "The NuRD chromatin-remodeling enzyme CHD4 promotes embryonic vascular integrity by transcriptionally regulating extracellular matrix proteolysis." dans: PLoS genetics, Vol. 9, Issue 12, pp. e1004031, (2013) (PubMed).

Curtis, Griffin: "The chromatin-remodeling enzymes BRG1 and CHD4 antagonistically regulate vascular Wnt signaling." dans: Molecular and cellular biology, Vol. 32, Issue 7, pp. 1312-20, (2012) (PubMed).

McDonel, Demmers, Tan, Watt, Hendrich: "Sin3a is essential for the genome integrity and viability of pluripotent cells." dans: Developmental biology, Vol. 363, Issue 1, pp. 62-73, (2012) (PubMed).

Shakya, Kang, Chumley, Williams, Tantin: "Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states." dans: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 450-9, (2011) (PubMed).

Ma, Lin, Bartolomei, Schultz: "Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted expression of H19 and Peg3 during mouse preimplantation development." dans: Biology of reproduction, Vol. 83, Issue 6, pp. 1027-35, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à CHD4

chromodomain helicase DNA binding protein 4 (CHD4), chromodomain helicase DNA binding protein 4a (chd4a), chromodomain helicase DNA binding protein 4b (chd4b), chromodomain helicase DNA binding protein 4 (chd4), chromodomain helicase DNA binding protein 4 (Chd4), chromodomain helicase DNA binding protein 4 L homeolog (chd4.L), 9530019N15Rik, AA617397, b230399n07, BC005710, CHD4, D6Ertd380e, im:7143343, MGC145363, Mi-2, Mi-2b, Mi-2beta, Mi2-BETA, mKIAA4075, si:ch211-51m24.3, si:ch211-57k11.10, wu:fb44b12, wu:fd12d03

Protein level used designations for CHD4

  • chromodomain helicase DNA binding protein 4
  • chromodomain-helicase-DNA-binding protein 4
  • ATP-dependent helicase CHD4
  • CHD-4
  • Mi-2 autoantigen 218 kDa protein
  • Mi-2 autoantigen
  • Mi-2 beta
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