CHEK1 Produits
(Checkpoint Kinase 1 (CHEK1))
Catégories
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].
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Catégories CHEK1 en vedette
CHEK1 Anticorps
High quality antibodies with extensive validation data.
CHEK1 Kits ELISA
Reliable ELISA kits for a wide range of species.
CHEK1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CHEK1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (1)
- (10)
N° du produit
ABIN6255201
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (7)
N° du produit
ABIN6255167
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (8)
N° du produit
ABIN6256255
Quantité
100 μL
Fiche technique
Fiche technique
CHEK1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954575
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380541
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380542
Quantité
2 x 96 tests
Fiche technique
Fiche technique
CHEK1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1349303
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Baculovirus infected Insect Cells
Validations
- (1)
N° du produit
ABIN7320012
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
N° du produit
ABIN7317105
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CHEK1
: "Sam68 is required for the growth and survival of nonmelanoma skin cancer." dans: Cancer medicine, Vol. 8, Issue 13, pp. 6106-6113, (2019) (PubMed).: "Serine/Threonine Kinase CHEK1-Dependent Transcriptional Regulation of RAD54L Promotes Proliferation and Radio Resistance in Glioblastoma." dans: Translational oncology, Vol. 11, Issue 1, pp. 140-146, (2018) (PubMed).
: "Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells." dans: Experimental cell research, Vol. 370, Issue 2, pp. 292-302, (2018) (PubMed).
: "Sterigmatocystin-induced checkpoint adaptation depends on Chk1 in immortalized human gastric epithelial cells in vitro." dans: Archives of toxicology, Vol. 91, Issue 1, pp. 259-270, (2017) (PubMed).
: "Two subunits of human ORC are dispensable for DNA replication and proliferation." dans: eLife, Vol. 5, (2017) (PubMed).
: "Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway." dans: PLoS pathogens, Vol. 13, Issue 3, pp. e1006266, (2017) (PubMed).
: "TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint." dans: BMC molecular biology, Vol. 17, pp. 3, (2016) (PubMed).
: "CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells." dans: Nucleic acids research, Vol. 43, Issue 5, pp. 2603-14, (2015) (PubMed).
: "Dietary NiCl₂ causes G₂/M cell cycle arrest in the broiler's kidney." dans: Oncotarget, Vol. 6, Issue 34, pp. 35964-77, (2015) (PubMed).
: "Over expression of hRad9 protein correlates with reduced chemosensitivity in breast cancer with administration of neoadjuvant chemotherapy." dans: Scientific reports, Vol. 4, pp. 7548, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à CHEK1
checkpoint kinase 1 (CHEK1), serine/threonine-protein kinase chk1 (ANI_1_2436074), serine/threonine-protein kinase chk1 (AOR_1_768154), serine/threonine-protein kinase Chk1 (PTRG_04183), CAMK/CAMKL/CHK1 protein kinase Chk1 (SJAG_01680), serine/threonine-protein kinase chk1 (PAAG_04978), serine/threonine-protein kinase chk1 (MCYG_03290), serine/threonine-protein kinase chk1 (VDBG_03742), checkpoint kinase 1 S homeolog (chek1.S), checkpoint kinase 1 (Chek1), checkpoint kinase 1 (chek1), An08g10320, AO090003000441, C85740, CHEK1, CHK1, chk1, Chk1, id:ibd2720, rad27, zgc:56093Protein level used designations for CHEK1
- CHK1 checkpoint homolog
- Serine/threonine-protein kinase Chk1-like protein
- serine/threonine-protein kinase Chk1
- serine/threonine-protein kinase chk1
- Checkpoint, S. pombe, homolog of, 1
- Chk1-S
- cell cycle checkpoint kinase
- checkpoint kinase-1
- Chk1 checkpoint kinase
- xChk1
- checkpoint kinase 1 homolog
- rad27 homolog
- 2720
- integral membrane protein 1
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